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NISTC19184679, identified as bis(2-ethylhexyl) phthalate or diethylhexyl phthalate (DEHP), is a colorless liquid with a mild, pleasant odor. It is widely recognized as a plasticizer in the manufacturing of a variety of consumer products. DEHP is known for its endocrine-disrupting properties and has been associated with several health risks, such as reproductive and developmental issues, and is considered a potential carcinogen. Due to these concerns, DEHP has faced regulatory actions and restrictions in many countries, prompting the search for safer alternatives.

19184-67-9

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19184-67-9 Usage

Uses

Used in Consumer Product Manufacturing:
NISTC19184679 is used as a plasticizer to enhance the flexibility and durability of materials in the production of various consumer products. This includes applications in food packaging, toys, medical devices, and vinyl flooring.
Used in the Plastics Industry:
In the plastics industry, NISTC19184679 is used as a plasticizer for the manufacturing of flexible polyvinyl chloride (PVC) products. It provides these products with increased flexibility, making them suitable for a range of applications.
Used in the Medical Device Industry:
NISTC19184679 is used as a plasticizer in the production of certain medical devices, where flexibility and durability are required. However, due to its potential health risks, there is an ongoing effort to find safer alternatives for use in medical applications.
Used in the Food Packaging Industry:
NISTC19184679 is used in the food packaging industry to improve the flexibility of packaging materials, ensuring better protection and preservation of food products. However, due to concerns about DEHP's endocrine-disrupting properties and potential health risks, there is a push for safer alternatives in this industry as well.
Used in the Toy Manufacturing Industry:
NISTC19184679 is used in the production of toys, particularly those made from PVC, to enhance their flexibility and durability. Given the potential health risks associated with DEHP, there is a growing demand for safer plasticizers in toy manufacturing to protect children's health.
Given the health concerns and regulatory restrictions associated with NISTC19184679, there is a significant focus on researching and developing safer alternatives for its various applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 19184-67-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,8 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19184-67:
(7*1)+(6*9)+(5*1)+(4*8)+(3*4)+(2*6)+(1*7)=129
129 % 10 = 9
So 19184-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H16O4/c1-9(2,5-7(10)12-3)6-8(11)13-4/h5-6H2,1-4H3

19184-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name dimethyl 3,3-dimethylpentanedioate

1.2 Other means of identification

Product number -
Other names dimethyl 3,3-dimethylglutaraye

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19184-67-9 SDS

19184-67-9Relevant academic research and scientific papers

Me2AlSEt-promoted domino dieckmann cyclization enables the total synthesis of polycyclic polyprenylated acylphloroglucinols

Wang, Liping,Sun, Lian,Wang, Xueying,Wu, Rong,Zhou, Hua,Zheng, Changwu,Xu, Hongxi

supporting information, p. 8075 - 8079 (2019/10/14)

A bioinspired, Me2AlSEt-promoted domino Dieckmann cyclization via an 8-membered ring intermediate to construct bicyclo[3.3.1]nonanes was developed, and the divergent syntheses of nine complex polycyclic polyprenylated acylphloroglucinols were a

BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS

-

Page/Page column 62, (2018/03/09)

Disclosed are compounds of Formula (I) to (IV): [INSERT CHEMICAL STRUCTURE HERE] or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof. Also disclosed are methods of using such compounds as PAR4 inhibitors, and pharmace

ANTIVIRAL COMPOUNDS

-

Paragraph 0985, (2018/04/13)

The present invention relates to novel compounds of general formula (I) wherein the groups X, and R1 to R4 have the meanings given in the description and claims, process for preparing these compounds and their use as for treating, preventing or ameliorating viral infections and their use for treating, preventing or ameliorating diseases which are associated with PLA2G16.

A general method for making peptide therapeutics resistant to serine protease degradation: Application to dipeptidyl peptidase IV substrates

Heard, Kathryn R.,Wu, Wengen,Li, Youhua,Zhao, Peng,Woznica, Iwona,Lai, Jack H.,Beinborn, Martin,Sanford, David G.,Dimare, Matthew T.,Chiluwal, Amrita K.,Peters, Diane E.,Whicher, Danielle,Sudmeier, James L.,Bachovchin, William W.

supporting information, p. 8339 - 8351 (2013/12/04)

Bioactive peptides have evolved to optimally fulfill specific biological functions, a fact which has long attracted attention for their use as therapeutic agents. While there have been some recent commercial successes fostered in part by advances in large-scale peptide synthesis, development of peptides as therapeutic agents has been significantly impeded by their inherent susceptibility to protease degradation in the bloodstream. Here we report that incorporation of specially designed amino acid analogues at the P1′ position, directly C-terminal of the enzyme cleavage site, renders peptides, including glucagon-like peptide-1 (7-36) amide (GLP-1) and six other examples, highly resistant to serine protease degradation without significant alteration of their biological activity. We demonstrate the applicability of the method to a variety of proteases, including dipeptidyl peptidase IV (DPP IV), dipeptidyl peptidase 8 (DPP8), fibroblast activation protein α (FAPα), α-lytic protease (αLP), trypsin, and chymotrypsin. In summary, the "P1′ modification" represents a simple, general, and highly adaptable method of generating enzymatically stable peptide-based therapeutics.

184. Stereoselective Hydrolysis of Substituted Cyclopropanedicarboxylates with Pig Liver Esterase

Walser, Paula,Renold, Peter,N'Goka, Victor,Hosseinzadeh, Fatemeh,Tamm, Christoph

, p. 1941 - 1952 (2007/10/02)

The hydrolysis of the meso-cyclopropane-1,2-dicarboxylates 1a-3a, 4, 5a, 6a, and 9, containing various substituents at C(3), and of the rac-3-phenylcyclopropane-1,2-dicarboxylates 7a, 8a, and 10 with pig liver esterase (PLE) is described.The stereoselectivity and absolute configurations of the products were determined.An interpretation of results was attempted on the basis of a recent active-site model for PLE.

Process for the production of 3,3-dimethylglutaric acid or its esters

-

, (2008/06/13)

Process for the production of 3,3-dimethylglutaric acid or its esters from dimedone. Dimedone is converted with ozone into an ozone-addition product. The latter is converted by hydrolysis into 3,3-dimethylglutaric acid or by alcoholysis into one of its esters.

INTRAMOLECULAR OXIDATIVE COUPLING OF THE BIS ENOLATE DERIVED FROM DIMETHYL β,β-DIMETHYLGLUTARATE: A FACILE STEREOSELECTIVE ROUTE TO A VERSATILE SYNTHON FOR PREPARATION OF INSECTICIDAL PYRETHROIDS

Babler, James H.,Haack, Richard A.

, p. 905 - 912 (2007/10/02)

Treatment of the bis enolate derived from dimethyl β,β-dimethylglutarate with silver chloride afforded dimethyl cis-3,3-dimethyl-1,2-cyclopropanedicarboxylate, a versatile synthon for the preparation of the acid component of cis-pyrethroids.A similar experiment utilizing iodine as the oxidant led to the isolation of the corresponding trans diester with good stereoselectivity.

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