191939-45-4Relevant academic research and scientific papers
The synthesis of α-fluoroketones by 1,4-additions of mono-fluorinated enamines to Michael acceptors
Bridge, Colin F.,O'Hagan, David
, p. 21 - 24 (2007/10/03)
Stork enamine reactions are explored with mono-fluorinated enamines derived from α-fluoroacetophenones and pyrrolidine. The resulting enamines react under mild conditions with Michael acceptors (acrylonitrile, methyl acrylate, methyl methacrylate, methyl vinyl ketone and cyclohexenone) to generate a variety of substituted α-fluoroketones.
