1920-54-3

Basic information

• Product Name: 6-chloro-2-(pyridin-3-yl)-4H-chromen-4-one
• CAS NO: 1920-54-3
• Molecular Formula: C₁₄H₈ClNO₂
• Molecular Weight: 257.6718
• Mol File: 1920-54-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 434.7°C at 760 mmHg
• Flash Point: 216.7°C
• Density: 1.396g/cm³
• Vapor Pressure: 9.27E-08mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 6-chloro-2-(pyridin-3-yl)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(pyridin-3-yl)-4H-chromen-4-one(1920-54-3)
• EPA Substance Registry System: 6-chloro-2-(pyridin-3-yl)-4H-chromen-4-one(1920-54-3)

Safety Data

• Hazardous Substances Data: 1920-54-3(Hazardous Substances Data)

Upstream product

• 59-67-6 nicotinic acid 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 7154-62-3 1-(5-chloro-2-hydroxyphenyl)-3-(pyridine-3-yl)propane-1,3-dione 
• 7209-62-3 Pyridin-3-carbonsaeure-(2-acetyl-4-chlor-phenylester) 
• 1218-25-3 1-(5-chloro-2-hydroxy-phenyl)-3-pyridin-3-yl-propenone 

Downstream Products

• 99698-74-5 4-Chloro-2-(7-pyridin-3-yl-2,3-dihydro-1H-[1,4]diazepin-5-yl)-phenol 

Relevant articles and documents

Synthesis and antimicrobial activity of 2-(pyridine-3-yl)-4 H -chromen-4-one derivatives

An efficiently synthesis of chromones via cyclodehydration of corresponding 1-(2-hydroxyphenyl)-3-(pyridine-3-yl)propane-1,3-dione is described under ultrasound irradiation. A series of novel 2-(pyridine-3-yl)-4H-chromen-4-one derivatives was confirmed on the basis of 1H-NMR, mass, IR spectral data, and elemental analysis. The synthesized compounds were evaluated for their antibacterial and antifungal activities. Most of the compounds were found to be comparable potent than the reference standard drugs. Utilization of ultrasound irradiation, simple reaction conditions, isolation, and purification makes this manipulation very interesting from an economic and environmental perspective.