7154-62-3 Usage
Source
Spice turmeric (Curcuma longa)
Appearance
Yellow crystalline solid
Solubility
Soluble in dimethyl sulfoxide (DMSO), ethanol, and acetone; slightly soluble in water
Chemical Structure
Contains two phenolic hydroxyl groups and a β-diketone system
Molecular Weight
398.83 g/mol
Functional Groups
Chloro, hydroxy, pyridine, and β-diketone
Color
Responsible for turmeric's characteristic yellow color
Traditional Medicine
Used for centuries for its anti-inflammatory, antioxidant, and potentially anticancer properties
Therapeutic Applications
Inflammatory conditions, neurological disorders, cardiovascular diseases, and cancer
Pharmacological Properties
Anti-inflammatory, antioxidant, anticancer, and antimicrobial activities
Preclinical and Clinical Studies
Shown promise in various studies for its potential therapeutic applications
Ongoing Research
Development of novel therapies and drug formulations due to its unique chemical structure and pharmacological properties
Bioavailability
Low bioavailability due to rapid metabolism
Challenges
Improving clinical application by developing various curcumin formulations and delivery systems to enhance efficacy and therapeutic potential
Safety
Generally considered safe for consumption, but may cause gastrointestinal upset in high doses or in sensitive individuals
Synergistic Effects
Curcumin's bioavailability and efficacy can be enhanced when combined with other compounds, such as piperine (found in black pepper)
Check Digit Verification of cas no
The CAS Registry Mumber 7154-62-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,5 and 4 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7154-62:
(6*7)+(5*1)+(4*5)+(3*4)+(2*6)+(1*2)=93
93 % 10 = 3
So 7154-62-3 is a valid CAS Registry Number.
7154-62-3Relevant articles and documents
Synthesis and antimicrobial activity of 2-(pyridine-3-yl)-4 H -chromen-4-one derivatives
Chate, Asha V.,Ghotekar, Dattatraya S.,Bhagat, Sunil S.,Gill, Charansingh H.
, p. 149 - 154 (2013/03/13)
An efficiently synthesis of chromones via cyclodehydration of corresponding 1-(2-hydroxyphenyl)-3-(pyridine-3-yl)propane-1,3-dione is described under ultrasound irradiation. A series of novel 2-(pyridine-3-yl)-4H-chromen-4-one derivatives was confirmed on the basis of 1H-NMR, mass, IR spectral data, and elemental analysis. The synthesized compounds were evaluated for their antibacterial and antifungal activities. Most of the compounds were found to be comparable potent than the reference standard drugs. Utilization of ultrasound irradiation, simple reaction conditions, isolation, and purification makes this manipulation very interesting from an economic and environmental perspective.
