192060-79-0

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 192060-77-8 Hexadecanoic acid (R)-1-hexadecanoyloxymethyl-2-{methoxy-[(1R,2S,3S,4R,5R,6S)-3,4,5-tris-(bis-benzyloxy-thiophosphoryloxy)-2,6-bis-methoxymethoxy-cyclohexyloxy]-phosphoryloxy}-ethyl ester 
• 1013649-43-8 1D-O-(1,2-di-O-palmitoyl-sn-(2S)glycerol-3-O-cyanoethylphospho)-3,4,5-(dicyanoethyl phosphothionate)-2,6-O-bis(methoxymethyl)-myo-inositol 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 

Relevant academic research and scientific papers

Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate

Metabolically-stabilized analogs of PtdIns(3,4,5)P3 have shown long-lived agonist activity for cellular events mediated by this phosphoinositide. We describe an efficient method for the total asymmetric synthesis of the trisphosphorothioate (PT

Synthesis of phosphorothioate analogs of phosphatidylinositol 3,4,5-trisphosphate

Phosphorothioate analogs of phosphatidylinositol 3,4,5-trisphosphate have been synthesized using Me3N-Me3SiCl reagent in a critical exhaustive cleavage of O-benzyl phosphorothioate triester intermediates.