25561-30-2 Usage
Uses
Different sources of media describe the Uses of 25561-30-2 differently. You can refer to the following data:
1. Used for synthesis of pharmaceutical intermediates.
2. Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
3. N,O-bis(trimethylsilyl)-trifluoroacetamide (BSTFA) is similar to BSA in specificity of modification and there are several studies which have used both reagents.One study found BSTFA superior to BSA in product stability and yield of derivative. Another study compared several trimethylsilyl donors for end-capping of silica and observed that BSTFA was more reactive than BSA but less reactive than TMCim. Both BSA and BSTFA were used to prepare trimethylsilyl derivatives of pyrimidines and purines.Current work has used BSTFA for metabolomics analysis of urine,for the measurement of khatamines (psychoactive amines of khat (Catha edulis Forsk), and for the measurement of acrylamide in cocoa.
4. N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.
Chemical Properties
Clear to yellowish clear liquid
Definition
ChEBI: A silyl ether that is the N,O-bis(trimethylsilyl) derivative of trifluoroacetamide. N,O-bis(trimethylsilyl)trifluoroacetamide is a derivatisation agent used in gas chromatography/m
ss spectrometry applications.
General Description
N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.
Check Digit Verification of cas no
The CAS Registry Mumber 25561-30-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,5,6 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 25561-30:
(7*2)+(6*5)+(5*5)+(4*6)+(3*1)+(2*3)+(1*0)=102
102 % 10 = 2
So 25561-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H18F3NOSi2/c1-14(2,3)8(9,15(4,5)6)7(13)12(10)11/h1-6H3
25561-30-2Relevant articles and documents
Carbacephalosporin compound, their preparation and use
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, (2008/06/13)
Carbacephalosporin compounds of formula (I), STR1 salts thereof, processes for their synthesis and uses thereof, wherein: R1 is hydrogen, methoxy or formamido; R2 is an acyl group; CO2 R3 is a carboxy group or a carboxylate anion, or R3 is a carboxy protecting group or a pharmaceutically acceptable salt-forming group or in vivo hydrolysable ester group; R4, R5, R6 and R7 represent hydrogen or a substituent; R4 and R7 may be replaced by a chemical bond between the two carbon atoms shown; R5 and R6 may be linked together into a cyclic system. The compounds (I) have antibacterial properties.
Bis-trimethylsilyl cefamandole and process therefor
-
, (2008/06/13)
Bis-trimethylsilyl cefamandole is useful for regenerating cefamandole of excellent purity.
