192061-04-4

Upstream product

• 178036-22-1 (2S-cis)-3-[[(4-methoxyphenyl)methoxy]methyl]-oxiranemethanol 
• 143833-81-2 (Z)-4-(4-methoxybenzyloxy)but-2-en-1-ol 
• 74076-63-4 2-(4-methoxyphenyl)-4,7-dihydro-1,3-dioxepine 
• 123-11-5 4-methoxy-benzaldehyde 
• 192061-01-1 (2S-cis)-methyl ester 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3-[(4-methoxyphenyl)methoxymethyl]-1-aziridinecarboxylic acid 
• 192061-02-2 (2S-cis)-methyl ester 2-(hydroxymethyl)-3-[(4-methoxyphenyl)methoxymethyl]-1-aziridinecarboxylic acid 
• 125229-14-3 methyl 3-methoxymethyloxy-4-methyl-5-nitrobenzene 
• 192061-03-3 (2S-cis)-methyl ester 2-formyl-3-[(4-methoxyphenyl)methoxymethyl]-1-aziridinecarboxylic acid 

Downstream Products

• 192061-05-5 [2S-(2α,3α)]-methyl ester 2-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(4-methoxycarbonyl)-2-(methoxymethoxy)-6-nitrophenyl]ethyl]-3-[[(4-methoxyphenyl)methoxy]methyl]-1-aziridinecarboxylic acid 
• 192061-08-8 [2S-(2α,3α)]-methyl ester 2-[2-[2-amino-4-(methoxycarbonyl)-6-(methoxymethoxy)phenyl]-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-3-formyl-1-aziridinecarboxylic acid 
• 192061-07-7 [2S-(2α,3α)]-methyl ester 2-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(4-methoxycarbonyl)-2-(methoxymethoxy)-6-nitrophenyl]ethyl]-3-formyl-1-aziridinecarboxylic acid 
• 192061-06-6 [2S-(2α,3α)]-methyl ester 2-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(4-methoxycarbonyl)-2-(methoxymethoxy)-6-nitrophenyl]ethyl]-3-(hydroxymethyl)-1-aziridinecarboxylic acid 
• 263138-97-2 (1aS,9aS)-3-[(4,5-dimethoxy-2-nitrophenyl)methyl] 5-methanol-1a,2,3,8,9,9a-hexahydro-7-(methoxymethoxy)-9-hydroxy-1H-aziridino[2,3-c][1]benzazocine-3-carboxylic acid 
• 192061-14-6 (1aS-cis)-3-[(4,5-dimethoxy-2-nitrophenyl)methyl] 1-methyl ester 5-formyl-1a,8,9a-tetrahydro-7-(methoxymethoxy)-9-oxo-1H-aziridino[2,3-c][1]benzazocine-1,3(2H)-dicarboxylic acid 
• 263138-94-9 (1aS,9aS)-3-[(4,5-dimethoxy-2-nitrophenyl)methyl] 1-methyl ester 5-methanol-1a,2,3,8,9,9a-hexahydro-7-(methoxymethoxy)-9-hydroxy-1H-aziridino[2,3-c][1]benzazocine-1,3(2H)-dicarboxylic acid 
• 263138-93-8 (1aS,9aS)-3-[(4,5-dimethoxy-2-nitrophenyl)methyl] 5-methanol-9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1a,2,3,8,9,9a-hexahydro-7-(methoxymethoxy)-1H-aziridino[2,3-c][1]benzazocine-3-carboxylic acid 
• 192061-10-2 (1aS,9aS)-3-[(4,5-dimethoxy-2-nitrophenyl)methyl] 1,5-dimethyl ester 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1a,2,3,8,9,9a-hexahydro-7-(methoxymethoxy)-1H-aziridino[2,3-c][1]benzazocine-1,3,5(2H)-tricarboxylic acid 
• 882304-56-5 9-(diethyl-isopropyl-silanyloxy)-7-methoxymethoxy-1a,8,9,9a-tetrahydro-2H-1,3-diaza-benzo[a]cyclopropa[e]cyclooctene-1,3,5-tricarboxylic acid 3-(4,5-dimethoxy-2-nitro-benzyl) ester 1,5-dimethyl ester 
• 1002328-89-3 4-methoxymethoxy-2-oxo-2,3,9,9a-tetrahydro-1aH-1,8-diaza-benzo[a]cyclopropa[e]cyclooctene-1,6,8-tricarboxylic acid 8-(4,5-dimethoxy-2-nitro-benzyl) ester 1,6-dimethyl ester 
• 477223-13-5 (2S,3R)-2-[1-(Diethyl-isopropyl-silanyloxy)-2-(4-methoxycarbonyl-2-methoxymethoxy-6-nitro-phenyl)-ethyl]-3-hydroxymethyl-aziridine-1-carboxylic acid methyl ester 
• 477223-15-7 (2S,3R)-2-[1-(Diethyl-isopropyl-silanyloxy)-2-(4-methoxycarbonyl-2-methoxymethoxy-6-nitro-phenyl)-ethyl]-3-formyl-aziridine-1-carboxylic acid methyl ester 
• 882304-48-5 (2S,3R)-2-[1-(Diethyl-isopropyl-silanyloxy)-2-(4-methoxycarbonyl-2-methoxymethoxy-6-nitro-phenyl)-ethyl]-3-(4-methoxy-benzyloxymethyl)-aziridine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and DNA cross-linking of a phototriggered FR900482 mitosene progenitor

(graph presented) The synthesis and biochemical reactivity of the first photoactivated mitosene-based DNA interstrand cross-linking agent is described.

Synthesis of the first photo-triggered pro-mitosene based on FR-900482

A stereocontrolled synthesis of an eight-membered ring precursor to a photo-triggered mitosene is described. (C) 2000 Elsevier Science Ltd.

Synthetic studies on FR 900482. Synthesis of a photo-triggered pro-mitosene

A stereocontrolled synthesis of an eight-membered ring precursor to a photo-triggered mitosene is described.