Journal of Medicinal Chemistry p. 4490 - 4498 (1994)
Update date:2022-08-04
Topics:
Chang, An-Chih
Takemori, Akira E.
Ojala, William H.
Gleason, William B.
Portoghese, Philip S.
2-(3,4-Dichlorophenyl)-N-methyl-N-<1-(3- or 4-substituted phenyl)-2-(1-pyrrolidinyl)ethyl>acetamides 3-6 were synthesized as κ-selective affinity labels and evaluated for opioid activity.In smooth muscle preparations, the non-electrophilic parent compound
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