192316-22-6Relevant articles and documents
Achievement of Bulky Homochirality in Zeolitic Imidazolate-Related Frameworks
Wang, Fei,Tang, Yu-Huan,Zhang, Jian
, p. 11064 - 11066 (2015)
Before this work, adding chiral C centers into zeolitic imidazolate frameworks (ZIFs) has never been realized. Presented here are the first examples on achieving bulky homochirality in ZIF systems, and three homochiral zeolitic imidazolate-related frameworks with sodalite and dia topologies are successfully synthesized by employing enantiopure imidazolate derivatives. The results open a new blueprint on the synthetic design of homochiral ZIFs for future applications.
Syntheses, Crystal Structures, and Spectral Characterization of Six Novel Benzimidazolyl Substituted Triaryltriazoles
Zhou, Yong-Fei,Zhang, Shi-Pei,Feng, Zhe,Shen, Xuan,Zhu, Dun-Ru
, p. 2773 - 2780 (2017/09/26)
Six new benzimidazolyl substituted triaryltriazoles, 3-(2-pyridyl)-4-(p-R-phenyl)-5-(2-benzimidazolyl)-1,2,4-triazoles (L1: R?=?OCH3; L2: R?=?CH3; L3: R?=?H; L4: R?=?Br; L5: R?=?Cl; L6: R?=?F) were successfully synthesized. Yield of L1–6 is in the range from 61 to 76%. The compounds L1–6 were characterized by UV–vis, FTIR, 1H-NMR, ESI-MS spectra, and elemental analysis. Additionally, the absolute configurations of L1–5 were determined by single crystal X-ray crystallography.
Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme
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Page/Page column 29, (2008/06/13)
Described herein are carbamate compounds. Such compounds are capable of modulating the activity of a checkpoint kinase, and described herein are methods for utilizing such modulation to treat cell proliferative disorders. Also described are pharmaceutical