192329-90-1

Basic information

• Product Name: [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE
• Synonyms: 4-(4-METHYPHENOXY)PHENYLSULFONYL CHLORIDE;4-(4-METHYLPHENOXY)BENZENESULFONYL CHLORIDE;[4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE
• CAS NO: 192329-90-1
• Molecular Formula: C₁₃H₁₁ClO₃S
• Molecular Weight: 282.74
• Product Categories: Phenyls & Phenyl-Het;Sulphonyl Chlorides;Phenyls & Phenyl-Het;Sulphonyl Chlorides
• Mol File: 192329-90-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE(192329-90-1)
• EPA Substance Registry System: [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE(192329-90-1)

Safety Data

• Hazard Codes: C,Xi
• Statements: 37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 192329-90-1(Hazardous Substances Data)

Usage

Description

[4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE is a chemical compound with the molecular formula C14H12ClO3S. It is a sulfonyl chloride derivative known for its use in organic synthesis as a reagent for introducing the sulfonyl chloride functional group into other molecules. This versatile building block in chemical synthesis can undergo various reactions such as nucleophilic substitution and aromatic substitution. However, it should be handled with care as it can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation.

Uses

Used in Pharmaceutical Industry:
[4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE is used as a reagent for the synthesis of various pharmaceuticals. Its ability to introduce the sulfonyl chloride functional group into molecules makes it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical industry, [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE is used as a reagent in the production of agrochemicals. Its role in introducing the sulfonyl chloride group aids in the creation of compounds that can be used in the development of pesticides, herbicides, and other agricultural products.
Used in Dye Industry:
[4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE is used as an intermediate in the synthesis of various dyes. Its sulfonyl chloride group contributes to the formation of dye molecules with specific color properties and stability.
Used in Organic Synthesis:
As a versatile building block in organic synthesis, [4-(4-METHYLPHENOXY)PHENYL]SULFONYL CHLORIDE is used for the synthesis of a wide range of organic compounds. Its ability to undergo nucleophilic substitution and aromatic substitution reactions makes it a valuable tool in the creation of new molecules for various applications.

Upstream product

• 79-37-8 oxalyl dichloride 
• 1706-12-3 4-phenoxytoluene 

Relevant articles and documents

Metalloproteinase inhibitors-compositions, uses preparation and intermediates thereof

The invention relates to compounds of the formula 1: wherein: Z is O or S; V is a divalent radical which together with C* and N forms a ring having six ring atoms, where each of said ring atoms other than C* and N independently is unsubstituted or substituted by a suitable substituent, and at least one of said other ring atoms is a heteroatom selected from O, N and S, and the remainder are carbon atoms; and Ar is an aryl or heteroaryl group; and pharmaceutically acceptable prodrugs, salts and solvates thereof. The invention further relates to pharmaceutically acceptable prodrugs, salts and solvates of these compounds. The invention also relates to methods of inhibiting the activity of metalloproteinases by administering a compound of the formula I or a prodrug, salt of solvate thereof. The invention further relates to pharmaceutical compositions comprising an effective amount of these compounds, prodrugs, salts, and solvates. The invention still further relates to methods and intermediates useful for preparing these compounds, prodrugs, salts, and solvates.

Metalloproteinase inhibitors and intermediates useful for their preparation

PCT No. PCT/US96/19328 Sec. 371 Date Jun. 29, 1998 Sec. 102(e) Date Jun. 29, 1998 PCT Filed Dec. 5, 1996 PCT Pub. No. WO97/20824 PCT Pub. Date Jun. 12, 1997The invention relates to compounds of formula (1) wherein: Z is O or S; V is a divalent radical which together with C* and N forms a ring having six ring atoms, where each of said ring atoms other than C* and N independently is unsubstituted or substituted by a suitable substituent, and at least one of said other ring atoms is a heteroatom selected from O, N and S, and the remainder is carbon atoms; and Ar is an aryl or heteroaryl group; and pharmaceutically acceptable prodrugs, salts and solvates thereof. The invention further relates to pharmaceutically acceptable prodrugs, salts and solvates of these compounds. The invention also relates to methods of inhibiting the activity of metalloproteinases by administering a compound of formula (1) or a prodrug, salt or solvate thereof. The invention further relates to pharmaceutical compositions comprising an effective amount of these compounds, prodrugs, salts, and solvates. The invention still further relates to methods and intermediates useful for preparing these compounds, prodrugs, salts, and solvates.