19241-15-7 Usage
Uses
Used in Chemical Research and Synthesis:
2,5-DIMETHYLPHENYL ISOTHIOCYANATE is used as a key intermediate in chemical research and synthesis for the development of new compounds and materials. Its unique chemical structure and reactivity make it a valuable component in the creation of pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-DIMETHYLPHENYL ISOTHIOCYANATE is used as a building block for the synthesis of various drugs. Its potential biological activity and reactivity contribute to the development of new therapeutic agents.
Used in Agrochemical Industry:
2,5-DIMETHYLPHENYL ISOTHIOCYANATE is utilized as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its potential insecticidal properties make it a valuable component in the development of effective crop protection products.
Used in Antimicrobial Applications:
2,5-DIMETHYLPHENYL ISOTHIOCYANATE has been studied for its potential antimicrobial properties. It is used as an active ingredient in the development of antimicrobial agents to combat various types of bacteria and fungi.
Used in Insecticidal Applications:
Due to its potential insecticidal properties, 2,5-DIMETHYLPHENYL ISOTHIOCYANATE is used in the development of insecticides to control and eliminate pests in various settings, including agriculture and household use.
Check Digit Verification of cas no
The CAS Registry Mumber 19241-15-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,4 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 19241-15:
(7*1)+(6*9)+(5*2)+(4*4)+(3*1)+(2*1)+(1*5)=97
97 % 10 = 7
So 19241-15-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NS/c1-7-3-4-8(2)9(5-7)10-6-11/h3-5H,1-2H3
19241-15-7Relevant academic research and scientific papers
Synthesis and antitumor activity of novel pyridazinone derivatives containing 1,3,4-thiadiazole moiety
Qin, Junhu,Zhu, Mei,Zhu, Hongmei,Zhang, Liqiong,Fu, Yihong,Liu, Jiamin,Wang, Zhenchao,OuYang, Guiping
, p. 592 - 599 (2020/03/16)
A series of novel pyridazinone derivatives containing the 1,3,4-thiadiazole moiety were synthesized and characterized by 1H NMR, 13C NMR, spectroscopies HRMS and IR. Among them, the structure of compound 5c (2-(Tert-butyl)?4-chloro-5-((5-((2-ethylphenyl)amino)?1,3,4-thiadiazol-2-yl)thio)pyridazin-3(2H)-One) was unambiguously confirmed via single crystal X-ray diffraction analysis. The inhibitory activity of all the target compounds against MGC-803 and Bcap-37 was determined by MTT assay, with doxorubicin (the inhibition rates were 95.5 ± 0.4% and 95.7 ± 1.0% respectively) as a control. The preliminary results showed that the inhibitory activity of compound 5n (2-(Tert-butyl)?4-chloro-5-((5-((3-fluorophenyl)amino)?1,3,4-thiadiazol-2-yl)thio)pyridazin-3(2H)-One) was superior to the others. The inhibition rates of MGC-803 and Bcap-37 cells were 86.3 ± 2.2% and 92.3 ± 0.6% at a concentration of 10 μmol/L, respectively. The preliminary structure-activity relationship showed that when the 2-position of the benzene ring was substituted by a methyl group, such as compound 5j (2-(Tert-butyl)?4-chloro-5-((5-((2,3-dimethylphenyl)amino)?1,3,4-thiadiazol-2-yl)thio)pyridazin-3(2H)-One), it exhibited good anticancer activity on MGC-803 cells. Besides, introducing fluorine, chlorine, or trifluoromethyl group onto the benzene ring, such as compound 5 m (2-(Tert-butyl)?4-chloro-5-((5-((4-(trifluoromethoxy)phenyl)amino)?1,3,4-thiadiazol-2-yl)thio)pyridazin-3(2H)-One), displayed good anticancer activity on MGC-803 and Bcap-37 cells.
