1927-04-4 Usage
Type
Synthetic organic compound
Common Use
Scientific research neurotoxin
Neurotoxicity
Potent neurotoxin targeting catecholaminergic neurons
Mechanism of Action
Causes oxidative stress and mitochondrial dysfunction
Application
Creation of animal models of Parkinson's disease
Target
Selectively destroys dopamine-producing neurons in the brain
Study Subject
Investigating the role of dopamine in physiological and pathological processes
Research Focus
Potential treatments for Parkinson's disease and other neurological disorders
Safety Precautions
Handle with caution, use only by trained professionals
Setting
Laboratory
Check Digit Verification of cas no
The CAS Registry Mumber 1927-04-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,2 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1927-04:
(6*1)+(5*9)+(4*2)+(3*7)+(2*0)+(1*4)=84
84 % 10 = 4
So 1927-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO3.ClH/c9-2-1-5-3-6(10)8(12)7(11)4-5;/h3-4,10-12H,1-2,9H2;1H
1927-04-4Relevant academic research and scientific papers
One-Electron Redox Potentials of Phenols. Hydroxy- and Aminophenols and Related Compounds of Biological Interest
Steenken, S.,Neta, P.
, p. 3661 - 3667 (2007/10/02)
The rate constants for reversible electron transfer between a series of substituted phenolate ions and anilines and various substituted phenoxyl or anilino radicals in aqueous solution were measured by observing the formation or depletion of the radicals involved.Nonequilibrium concentrations of the radicals were produced in the presence of the corresponding phenols or anilines by using the pulse radiolysis technique.The relaxation of the system to equilibrium was monitored by optical detection methods.From the equilibrium constants for one-electron transfer, the one-electron redox potentials (E2) for 38 phenolic or anilino type compounds were determined, many of which are natural products.The redox potentials are strongly influenced by electron-donating or -withdrawing substituents at the aromatic system.
