1927-70-4

Basic information

• Product Name: 2-(1-Methylethoxy)tetrahydro-2H-pyran
• Synonyms: 2-(1-Methylethoxy)tetrahydro-2H-pyran;2-Isopropoxytetrahydro-2H-pyran;Tetrahydro-2-(1-methylethoxy)-2H-pyran;Tetrahydro-2-(isopropyloxy)-2H-pyran;Tetrahydro-2-isopropoxy-2H-pyran;Tetrahydro-2-isopropyloxy-2H-pyran
• CAS NO: 1927-70-4
• Molecular Formula: C₈H₁₆O₂
• Molecular Weight: 144.2114
• Mol File: 1927-70-4.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 167°Cat760mmHg
• Flash Point: 43.9°C
• Appearance: /
• Density: 0.92g/cm³
• Vapor Pressure: 2.29mmHg at 25°C
• Refractive Index: 1.431
• CAS DataBase Reference: 2-(1-Methylethoxy)tetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Methylethoxy)tetrahydro-2H-pyran(1927-70-4)
• EPA Substance Registry System: 2-(1-Methylethoxy)tetrahydro-2H-pyran(1927-70-4)

Safety Data

• Hazardous Substances Data: 1927-70-4(Hazardous Substances Data)

Usage

General Description

2-(1-Methylethoxy)tetrahydro-2H-pyran, also known as Methyltetrahydropyranyl ether, is a chemical compound that belongs to the class of tetrahydropyrans. It is commonly used as a solvent and a fragrance ingredient in various products. This chemical has a fruity, sweet odor and is often used in the production of perfumes, soaps, and other personal care products. It is also used as a flavoring agent in the food industry. Additionally, it can be used as an intermediate in the synthesis of other organic compounds due to its unique chemical properties. However, it is important to handle this chemical with caution as it can be harmful if ingested or inhaled and can cause skin and eye irritation.

InChI:InChI=1/C8H16O2/c1-7(2)10-8-5-3-4-6-9-8/h7-8H,3-6H2,1-2H3

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 67-63-0 isopropyl alcohol 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 151909-91-0 isopropyl 2,3,4,6-tetra-O-benzyl-D-glucopyranoside 
• 2307-69-9 toluene-4-sulfonic acid isopropyl ester 
• 67-63-0 isopropyl alcohol 
• 59556-68-2 isopropyl 2,3,5-tri-O-benzoyl-β-D-ribofuranoside 

Relevant articles and documents

Cyclopropenium Enhanced Thiourea Catalysis

An integral part of modern organocatalysis is the development and application of thiourea catalysts. Here, as part of our program aimed at developing cyclopropenium catalysts, the synthesis of a thiourea-cyclopropenium organocatalyst with both cationic hydrogen-bond donor and electrostatic character is reported. The utility of the this thiourea organocatalyst is showcased in pyranylation reactions employing phenols, primary, secondary, and tertiary alcohols under operationally simple and mild reaction conditions for a broad substrate scope. The addition of benzoic acid as a co-catalyst facilitating cooperative Br?nsted acid catalysis was found to be valuable for reactions involving phenols and higher substituted alcohols. Mechanistic investigations, including kinetic and 1H NMR binding studies in conjunction with density function theory calculations, are described that collectively support a Br?nsted acid mode of catalysis.

Facile O-glycosylation of glycals using Glu-Fe3O4-SO3H, a magnetic solid acid catalyst

A new glucose derived magnetic solid acid catalyst (Glu-Fe3O4-SO3H) was synthesized in a convenient and ecofriendly manner and well characterized using FTIR, PXRD, EDAX, SEM, and XPS which showed the presence of Fe3/

Direct glycosylation of unprotected and unactivated carbohydrates under mild conditions

Ligand exchange acetalization of acetals in the presence of catalytic amounts of mandelic acid and titanium tert-butoxide is reported. This transformation is successfully extended to glycosylation of unprotected and unactivated pentoses. Even unreactive pentoses such as d-arabinose or d-lyxose can be transformed by this new methodology into corresponding isopropyl glycosides.