19282-39-4

Basic information

• Product Name: ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE
• Synonyms: RARECHEM AK MA K008;ETHYL 5-PHENYLTHIOPHENE-2-CARBOXYLATE;ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE
• CAS NO: 19282-39-4
• Molecular Formula: C₁₃H₁₂O₂S
• Molecular Weight: 232.3
• Mol File: 19282-39-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 31-33°
• Boiling Point: 364.6°Cat760mmHg
• Flash Point: 174.3°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 1.67E-05mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE(19282-39-4)
• EPA Substance Registry System: ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE(19282-39-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 19282-39-4(Hazardous Substances Data)

Usage

General Description

ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE is a chemical compound with the molecular formula C13H12O2S. It is an ester derivative of 2-thiophenecarboxylic acid and is commonly used in organic synthesis and pharmaceutical research. ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE is characterized by its aromatic and ester functional groups, making it suitable for the development of various drugs and organic compounds. It is also known for its potential biological activities and may be used as a starting material for the synthesis of other organic compounds with similar structures. However, as with any chemical compound, proper handling and safety precautions should be observed when working with ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE.

InChI:InChI=1/C13H12O2S/c1-2-15-13(14)12-9-8-11(16-12)10-6-4-3-5-7-10/h3-9H,2H2,1H3

Upstream product

• 5187-82-6 (ethoxycarbonylmethyl)dimethylsulfonium bromide 
• 5751-83-7 ethyl 5-bromothiophene-2-carboxylate 
• 98-80-6 phenylboronic acid 
• 98-86-2 acetophenone 
• 30786-98-2 3-methylsulfanyl-3-phenylprop-2-enal 
• 33603-87-1 β-chlorocinnamaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 33603-87-1 (Z)-3-chloro-3-phenyl-2-propenal 

Downstream Products

• 52172-51-7 5-phenylthiophene-2-carbohydrazide 
• 439108-60-8 2-hydroxymethyl-5-phenylthiophene 
• 19163-21-4 5-phenylthiophene-2-carboxaldehyde 

Relevant articles and documents

Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity

Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of indivi

Oxazolidinone compound containing piperazine hydrazone structure

The invention discloses an oxazolidinone compound containing a piperazine hydrazone structure. The oxazolidinone compound comprises a compound shown as a general formula (I), or stereisomer thereof, or pharmaceutically-acceptable salt thereof, or solvate thereof or prodrug thereof, wherein R1 is hydrogen, fluorine, chlorine or trifluoromethyl, R2 is -NHCOCH3 or -OH, R3 is Ar which is C5-C10 aryl substituted by any 1-3 R4 and heteroaryl, and R4 is hydrogen, hydroxyl, halogen, nitro, amino, cyan, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkyl substituted by hydroxyl, amino or halogen, C1-C6 alkoxy substituted by hydroxyl, amino or halogen, amino substituted by mono- or bi-(C1-C6 alkyl), C1-C6 alkyl amido, free, salty, esterified and amidated hydroxyl, C1-C6 alkyl sulfinyl, C1-C6 alkyl sulfonyl, C1-C6 alkyl acyl and carbamoyl. The oxazolidinone compound can be used for preparing drug for treating microbial infection.

Synthesis, cytotoxicity and effects of some 1,2,4-triazole and 1,3,4-thiadiazole derivatives on immunocompetent cells

Novel derivatives of 4,5-substituted-1,2,4-triazole-thiones and 2,5-substituted-1,3,4-thiadiazoles were synthesized and evaluated for their cytotoxicity. The biological study indicated that compounds 4-ethyl-5-(4,5,6,7-tetrahydro-1-benzothien-2-yl)-2,4-di