19282-39-4

Usage

Uses

Used in Organic Synthesis:
ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE is used as a key intermediate in the synthesis of various organic compounds. Its aromatic and ester functional groups make it a versatile building block for the development of new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE is used as a starting material for the development of new drugs. Its potential biological activities and structural features make it a promising candidate for the creation of novel therapeutic agents.
Used in the Synthesis of Other Organic Compounds:
ETHYL 5-PHENYL-2-THIOPHENECARBOXYLATE can be used as a starting material for the synthesis of other organic compounds with similar structures. Its unique properties and reactivity make it a valuable component in the design and synthesis of new molecules with potential applications in various industries.

InChI:InChI=1/C13H12O2S/c1-2-15-13(14)12-9-8-11(16-12)10-6-4-3-5-7-10/h3-9H,2H2,1H3

Upstream product

• 5187-82-6 (ethoxycarbonylmethyl)dimethylsulfonium bromide 
• 5751-83-7 ethyl 5-bromothiophene-2-carboxylate 
• 98-80-6 phenylboronic acid 
• 98-86-2 acetophenone 
• 30786-98-2 3-methylsulfanyl-3-phenylprop-2-enal 
• 33603-87-1 β-chlorocinnamaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 33603-87-1 (Z)-3-chloro-3-phenyl-2-propenal 

Downstream Products

• 52172-51-7 5-phenylthiophene-2-carbohydrazide 
• 439108-60-8 2-hydroxymethyl-5-phenylthiophene 
• 19163-21-4 5-phenylthiophene-2-carboxaldehyde 

Relevant academic research and scientific papers

Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity

Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of indivi

URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE

This disclosure relates to uridine nucleoside derivatives, compositions comprising therapeutically effective amounts of those nucleoside derivatives and methods of using those nucleoside derivatives or compositions in treating disorders that are responsive to compounds, such as agonists, of P2Y6 receptor, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease) and traumatic CNS injury, pain, Down Syndrome (DS), glaucoma and inflammatory conditions.

Oxazolidinone compound containing piperazine hydrazone structure

The invention discloses an oxazolidinone compound containing a piperazine hydrazone structure. The oxazolidinone compound comprises a compound shown as a general formula (I), or stereisomer thereof, or pharmaceutically-acceptable salt thereof, or solvate thereof or prodrug thereof, wherein R1 is hydrogen, fluorine, chlorine or trifluoromethyl, R2 is -NHCOCH3 or -OH, R3 is Ar which is C5-C10 aryl substituted by any 1-3 R4 and heteroaryl, and R4 is hydrogen, hydroxyl, halogen, nitro, amino, cyan, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkyl substituted by hydroxyl, amino or halogen, C1-C6 alkoxy substituted by hydroxyl, amino or halogen, amino substituted by mono- or bi-(C1-C6 alkyl), C1-C6 alkyl amido, free, salty, esterified and amidated hydroxyl, C1-C6 alkyl sulfinyl, C1-C6 alkyl sulfonyl, C1-C6 alkyl acyl and carbamoyl. The oxazolidinone compound can be used for preparing drug for treating microbial infection.

Base catalyzed reaction of ethyl thioglycolate with β-aryl-β-(methylthio) acroleins: A general method for the synthesis of 2-carbethoxy-5-substituted/4,5-annulated thiophenes in high overall yields

(Methylthio) acroleins 1a-m were shown to be stable unlike their counterpart the chloroacroleins and their efficacy as 1,3-dielectrophilic properties have now been examined successfully in this work. They are shown to react with ethyl thioglycolate in the

Synthesis, cytotoxicity and effects of some 1,2,4-triazole and 1,3,4-thiadiazole derivatives on immunocompetent cells

Novel derivatives of 4,5-substituted-1,2,4-triazole-thiones and 2,5-substituted-1,3,4-thiadiazoles were synthesized and evaluated for their cytotoxicity. The biological study indicated that compounds 4-ethyl-5-(4,5,6,7-tetrahydro-1-benzothien-2-yl)-2,4-di

Microwave assisted synthesis of 5-arylthiophene-2-carboxylates

A simple and rapid method for the synthesis of 5-Aryl-thiophene-2- carboxylates 3 has been developed by the condensation of β-chlorovinyl aldehydes 1 with mercaptoacetic acid esters 2 under microwave irradiation conditions.