192864-01-0Relevant academic research and scientific papers
Synthesis of 9-[2',3'-dideoxy-2',3'-bis-C-hydroxymethyl-α-L-threofuranosyl] adenine and its 4'-thio analog as potential antiviral agents
Kikuchi, Yoshiko,Kurata, Hiroko,Nishiyama, Shigeru,Yamamura, Shosuke,Kato, Kuniki
, p. 4795 - 4798 (2007/10/03)
The enantiomerically pure synthesis or 9-[2',3'-dideoxy-2',3'-bis-C-hydroxymethyl-α-L- threofuranosyl]adenine and its 4'-thio analog was achieved via coupling of silylated 6-chloropurine with 1-O-acetylfuronase derivative 17 and its 4'-thio analog 24, respectively, prepared from (+)-diethyl L-tartrate.
