192870-66-9Relevant academic research and scientific papers
FeCl3·6H2O/acetaldehyde, a versatile system for the deprotection of ketals and acetals via a transacetalization process
Schiavo, Lucie,Jeanmart, Lo?c,Lanners, Steve,Choppin, Sabine,Hanquet, Gilles
, p. 1421 - 1424 (2017/02/23)
Mild and efficient catalytic deprotection of ketals/acetals mediated by FeCl3·6H2O/acetaldehyde has been described in this paper. The versatility and high chemoselectivity of the iron(iii)/aldehyde system are demonstrated by a large scope of examples. Deprotected ketones/aldehydes are nearly quantitatively isolated after filtration over a pad of silica gel followed by evaporation of volatile by-products.
An expeditious synthesis of N-acetylneuraminic acid α-C-glycosyl derivatives ("α-C-glycosides") from the anomeric acetates
Malapelle, Adeline,Coslovi, Anna,Doisneau, Gilles,Beau, Jean-Marie
, p. 3145 - 3157 (2008/02/09)
The reductive metallation of the readily available peracetylated derivatives of methyl N-acetylneuraminate 3a and 3b by samarium diiodide without any additive generates the corresponding anomeric samarium(III) organometallics. These intermediates react ef
New bioorganic reagents: Evolved cyclohexanone monooxygenase - Why is it more selective?
Kayser, Margaret M.,Clouthier, Christopher M.
, p. 8424 - 8430 (2007/10/03)
Four mutants of the cyclohexanone monooxygenase (CHMO) evolved as catalysts for Baeyer-Villiger oxidation of 4-hydroxycyclohexanone were investigated as catalysts for a variety of 4-substituted and 4,4-disubstituted cyclohexanones. Several excellent catalytic matches (mutant/substrate) were identified. The most important, however, is the finding that, in a number of cases, a mutant with a single exchange, Phe432Ser, was shown to be as robust and more selective as a catalyst than the wild-type CHMO. All biotransformations were performed on a laboratory scale, allowing full characterization of the products. The absolute configurations of two products were established. A model suggesting a possible role of the 432 serine residue in enantioselectivity control is proposed.
SUBSTITUTED SPIROCYCLIC KETOENOLS
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Page/Page column 132, (2008/06/13)
The invention relates to novel substituted spirocyclic ketoenols of formula (I), wherein W, X, Y, Z, A, B, D, and G have the meaning indicated above, several methods for the production thereof, and the use thereof as pesticides, microbiocides, and herbici
1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
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, (2008/06/13)
1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds, methods of preparing them and the use of these compounds in drugs are described.
