192987-77-2

Upstream product

• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-42-5 styrene 
• 103548-09-0 (S)-2-((tert-butyldimethylsilyl)oxy)-1-phenylethan-1-ol 
• 74-88-4 methyl iodide 

Downstream Products

• 66051-01-2 (S)-2-methoxy-2-phenylethanol 
• 1457952-44-1 (S)-2-methoxy-2-phenylethyl-1 H-imidazole-1-carboxylate 
• 1457952-47-4 bis((S)-2-methoxy-2-phenylethyl) carbonate 
• 1457952-50-9 (R)-2-methoxy-2-phenylethyl((S)-2-methoxy-2-phenylethyl) carbonate 
• 1457952-48-5 (S)-2-methoxy-1-phenylethyl((S)-2-methoxy-2-phenylethyl) carbonate 
• 26164-26-1 (S)-2-methoxy-2-phenylacetic acid 

Relevant academic research and scientific papers

Microstructure analysis of a CO2 copolymer from styrene oxide at the diad level

A large amount of interesting information on the alternating copolymerization of CO2 with terminal epoxides has already been reported, such as the regiochemistry of epoxide ring-opening and the stereochemistry of the carbonate unit sequence in the polymer chain. Moreover, the microstructures of CO2 copolymers from propylene oxide and cyclohexene oxide have also been well-studied. However, the microstructure of the CO2 copolymer from styrene oxide (SO), an epoxide that contains an electron-withdrawing group, has not yet been investigated. Herein, we focus on the spectroscopic assignment of the CO2 copolymer from styrene oxide at the diad level by using three kinds of model dimer compounds, that is, T-T, H-T, and H-H. By comparing the signals in the carbonyl region, we concluded that the signals at δ=154.3, 153.8, and 153.3 ppm in the 13C NMR spectrum of poly(styrene carbonate) were due to tail-to-tail, head-to-tail, and head-to-head carbonate linkages, respectively. Moreover, various isotactic and syndiotactic model compounds based on T-T, H-T, and H-H (dimers (R,R)-T-T, (S,S)-T-T, and (R,S)-T-T; (R,R)-H-T, (S,S)-H-T, and (R,S)-H-T; (R,R)-H-H, (S,S)-H-H, and (R,S)-H-H) were synthesized for the further spectroscopic assignment of stereospecific poly(styrene carbonate)s. We found that the carbonate carbon signals were sensitive towards the stereocenters on adjacent styrene oxide ring-opening units. These discoveries were found to be well-matched to the microstructures of the stereoregular poly(styrene carbonate)s that were prepared by using a multichiral CoIII-based catalyst system. T-T races: The spectroscopic assignment of regio- and stereoregular poly(styrene carbonate)s at the diad level was performed by 13C NMR studies of three kinds of model compounds, as well as their syndiotactic (R,S) and isotactic (R,R or S,S) dimers. Copyright

Enantioselective synthesis of arylmethoxyacetic acid derivatives

The preparation of several arylmethoxyacetic acids by a sequence of asymmetric dihydroxylation and further oxidation of the resulting glycol with TEMPO/NaClO/NaClO2 is described. The scope and limitations of the reaction are discussed.