193286-95-2Relevant academic research and scientific papers
An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran
Preville, Patrice,He, John X.,Tarazi, Micheline,Siddiqui, M. Arshad,Cody, Wayne L.,Doherty, Annette M.
, p. 1563 - 1566 (2007/10/03)
Inogatran is an effective and selective pseudopeptide inhibitor of thrombin that has been shown to be efficacious in a series of in vitro and in vivo models of thrombosis. Herein, we report an efficient and convergent chemical synthesis of Inogatran that is amenable to the preparation of multiple gram quantities.
