193287-01-3

Upstream product

• 193286-99-6 C₃₁H₄₁N₅O₇ 
• 168827-78-9 C₂₅H₃₂N₄O₆ 
• 193286-96-3 (R)-2-(Benzyloxycarbonyl-benzyloxycarbonylmethyl-amino)-3-cyclohexyl-propionic acid tert-butyl ester 
• 193286-95-2 (R)-2-(Benzyloxycarbonylmethyl-amino)-3-cyclohexyl-propionic acid tert-butyl ester 
• 193286-94-1 (R)-2-Amino-3-cyclohexyl-propionic acid tert-butyl ester 
• 3081-28-5 D-phenylalanine tert-butyl ester 
• 673-06-3 D-(R)-phenylalanine 

Relevant academic research and scientific papers

An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran

Inogatran is an effective and selective pseudopeptide inhibitor of thrombin that has been shown to be efficacious in a series of in vitro and in vivo models of thrombosis. Herein, we report an efficient and convergent chemical synthesis of Inogatran that is amenable to the preparation of multiple gram quantities.