1934-93-6

Basic information

• Product Name: 1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline
• Synonyms: 1-(4-Methoxybenzyl)-2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline;1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(4-methoxybenzyl)-2-methylisoquinoline;6,7-Dimethoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline;O-Methylarmepavine
• CAS NO: 1934-93-6
• Molecular Formula: C₂₀H₂₅NO₃
• Molecular Weight: 327.42
• Mol File: 1934-93-6.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline(1934-93-6)
• EPA Substance Registry System: 1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline(1934-93-6)

Safety Data

• Hazardous Substances Data: 1934-93-6(Hazardous Substances Data)

Usage

General Description

1,2,3,4-Tetrahydro-1-(4-methoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline, also known as AMMI, is a chemical compound with a complex structure consisting of multiple functional groups. It is a member of the isoquinoline alkaloid family and is derived from plants. AMMI has been studied for its potential pharmacological activities, including anti-inflammatory, analgesic, and neuroprotective properties. Its structure and properties make it an interesting target for pharmaceutical research and drug development. However, further studies are needed to fully understand its potential medicinal uses and explore its applications in the field of medicine.

Upstream product

• 3991-23-9 6,7-dimethoxy-1-(4-methoxy-benzyl)-2-methyl-3,4-dihydro-isoquinolinium; iodide 
• 186581-53-3 diazomethane 
• 1253195-04-8 6-demethyl-4'-O-methyl-N-methylcoclaurine 
• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 51714-24-0 6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile 
• 2746-25-0 p-Methoxybenzyl bromide 
• 1246431-52-6 C₁₉H₁₇Cl₃O₇ 
• 1580442-46-1 C₅₃H₅₈N₂O₈ 
• 1421820-27-0 N-[2-(3,4-dimethoxyphenyl)ethyl]-N-[1-((1S)-phenyl)ethyl]-2-(4-methoxyphenyl)acetamide 
• 104-01-8 4-Methoxyphenylacetic acid 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 228271-22-5 6,7-dimethoxy-1-[[4-[5-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinyl)methyl-2-methoxy]phenoxy]benzyl]-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 409366-27-4 (3,5-dichloro-4-hydroxyphenyl)acetic acid methyl ester 
• 114105-51-0 (S)-(-)-[2-(3,4-dimethoxyphenyl)ethyl](1-phenylethyl)amine 

Downstream Products

• 35854-35-4 4-[(4-methoxyphenyl)methyl]pyridine 
• 308803-68-1 methyl N-[2-(4,5-dimethoxy-2-[2-(4-methoxyphenyl)ethyl]phenyl)ethyl]-N-methylcarbamate 
• 102759-47-7 polysignine 
• 308803-66-9 (E)-methyl N-[2-(4,5-dimethoxy-2-[2-(4-methoxyphenyl)ethenyl]phenyl)ethyl]-N-methylcarbamate 

Relevant articles and documents

Light-Induced Alkylation of (Hetero)aromatic Nitriles in a Transition-Metal-Free C-C-Bond Metathesis

A light-induced C-C-σ-bond metathesis was achieved through transition-metal-free activation of an unstrained C(sp3)-C(sp3)-σ-bond in 1-benzyl-1,2,3,4-tetrahydroisoquinolines. A photoredox-mediated single-electron oxidation of these precursor amines yield radical cations which undergo a homolytic cleavage of a C(sp3)-C(sp3)-σ-bond rather than the well-known α-C-H-scission. The resulting carbon-centered radicals are used in the ipso-substitution of (hetero)aromatic nitriles proceeding through another single-electron transfer-mediated C-C-bond cleavage and formation.

Synthesis of (+)-O-methylthalibrine by employing a stereocontrolled Bischler-Napieralski reaction and an electrochemically generated diaryl ether

An efficient electrochemical four-step route was developed for the preparation of diaryl ether derivatives by using halogenation and dehalogenation processes in addition to electrochemical phenolic oxidation and reduction reactions. The synthesis of (+)-O

Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro

Forty-one isoquinoline alkaloids were tested for antiplatelet aggregation effects. Among them, (-)-discretamine (6), protopine (7), ochotensimine (18), O-methylarmepavinemethine (23), lindoldhamine (25), isotetrandrine (26), thalicarpine (27), papaverine (28), and D-(+)-N-norarmepavine (32) exhibited significant inhibitory activity towards adenosine 5′-diphosphate (ADP)-, arachidonic acid (AA)-, collagen-, and/or platelet-activating factor (PAF)-induced platelet aggregation. The results are discussed on the basis of structure-activity relationships. Georg Thieme Verlag KG Stuttgart.