193533-92-5

Usage

Uses

1. Used in Chemical Synthesis:
2,3,4-Trifluorotoluene is used as a building block for the synthesis of various fluorinated organic compounds. Its unique structure and reactivity make it a valuable intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals.
2. Used in Material Science:
In the field of material science, 2,3,4-trifluorotoluene is utilized as a precursor for the development of advanced materials with specific properties, such as enhanced thermal stability, chemical resistance, and improved mechanical strength.
3. Used in Pharmaceutical Industry:
2,3,4-Trifluorotoluene is employed as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those with fluorinated structures. These compounds often exhibit improved pharmacokinetic and pharmacodynamic properties, leading to better drug efficacy and safety profiles.
4. Used in Agrochemical Industry:
In the agrochemical industry, 2,3,4-trifluorotoluene is used as a starting material for the development of novel pesticides and herbicides with enhanced selectivity, reduced environmental impact, and improved efficacy against target pests.
5. Used in Fluoropolymer Production:
2,3,4-Trifluorotoluene serves as a monomer in the production of fluoropolymers, which are known for their exceptional chemical resistance, thermal stability, and non-stick properties. These polymers find applications in various industries, including automotive, aerospace, electronics, and consumer goods.

InChI:InChI=1/C7H5F3/c1-4-2-3-5(8)7(10)6(4)9/h2-3H,1H3

Upstream product

• 77-78-1 dimethyl sulfate 
• 176317-02-5 1-bromo-2,3,4-trifluorobenzene 
• 3862-73-5 2,3,4-trifluoroaniline 
• 1489-53-8 1,2,3-trifluorobenzene 

Downstream Products

• 244104-65-2 tert-butyl (3-bromo-4-tert-butoxycarbonylaminophenyl)carbamate 
• 24109-06-6 N-t-butylcarbonyl-4-bromoaniline 
• 959865-75-9 2,3-difluorobenzyl radical 
• 939439-07-3 3,4-difluorobenzyl radical 
• 131818-17-2 tert-butyl (4-bromophenyl)carbamate 
• 194782-91-7 (Z)-3-Cyclopropylamino-2-(2,3,4-trifluoro-5-methyl-6-nitro-benzoyl)-acrylic acid ethyl ester 
• 194782-90-6 3-Oxo-3-(2,3,4-trifluoro-5-methyl-6-nitro-phenyl)-propionic acid ethyl ester 
• 194782-89-3 2,3,4-Trifluoro-5-methyl-6-nitro-benzoic acid 
• 65829-28-9 2,3,4-Trifluor-5-methylbenzoesaeure 
• 193533-94-7 1-(2,3,4-Trifluoro-5-methyl-phenyl)-ethanone 

Relevant academic research and scientific papers

Friedel–Crafts Type Methylation with Dimethylhalonium Salts

The dimethylchloronium salt [Me2Cl][Al(OTeF5)4] is used to methylate electron-deficient aromatic systems in Friedel–Crafts type reactions as shown by the synthesis of N-methylated cations, such as [MeNC5F5]+, [MeNC5F4I]+, and [MeN3C3F3]+. To gain a better understanding of such fundamental Friedel–Crafts reactions, the role of the dimethylchloronium cation has been evaluated by quantum-chemical calculations.

BIODEGRADABLE INTRAVAGINAL DEVICES FOR DELIVERY OF THERAPEUTICS

The present disclosure relates to biodegradable intravaginal rings for the delivery of therapeutic or prophylactic agent, inter alia, antiviral agents. The present disclosure further relates to biodegradable polyurethanes which will allow therapeutic/prophylactic agents to be released in a controlled manner that will not degrade when in use, but will degrade upon disposal.

Novel 5-amino-6-methylquinolone antibacterials: A new class of non-6-fluoroquinolones

A novel 5-amino-6-methylquinoline carboxylic acid was synthesized from 2,3,4-trifluoro aniline in 12 steps and coupled with various types of amines to furnish new quinolone antibacterial agents. Depending on the structure of amine, some of quinolones showed comparable activity to ciprofloxacin or better Gram positive activity than ciprofloxacin, demonstrating that the C6 fluorine atom is not a necessary requirement for good antibacterial potency.