19357-64-3

Basic information

• Product Name: (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one
• Synonyms: (3E)-3-(3-Oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one; 1(3H)-isobenzofuranone, 3-(3-oxo-1(3H)-isobenzofuranylidene)-, (3E)-; 1(3H)-Isobenzofuranone, 3-(3-oxo-1(3H)-isobenzofuranylidene)-, (E)-
• CAS NO: 19357-64-3
• Molecular Formula: C₁₆H₈O₄
• Molecular Weight: 264.2323
• Mol File: 19357-64-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 440.3°C at 760 mmHg
• Flash Point: 230.3°C
• Density: 1.509g/cm³
• Vapor Pressure: 5.95E-08mmHg at 25°C
• Refractive Index: 1.714
• CAS DataBase Reference: (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one(19357-64-3)
• EPA Substance Registry System: (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one(19357-64-3)

Safety Data

• Hazardous Substances Data: 19357-64-3(Hazardous Substances Data)

Usage

General Description

The chemical compound (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one is a derivative of benzofuran, a heterocyclic compound commonly found in various natural products and pharmaceuticals. It is a yellow crystalline substance with a molecular formula of C16H8O3. (3E)-3-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-benzofuran-1(3H)-one has potential applications in the pharmaceutical industry as a building block for the synthesis of biologically active molecules. Its structure contains both a benzofuran and a benzophenone moiety, which makes it a versatile starting material for the development of new chemical entities with potential pharmacological activities. Further research and studies are needed to explore its full potential and applications in various fields.

Upstream product

• 85-44-9 phthalic anhydride 
• 42116-85-8 Tributyl-(3-oxo-1,3-dihydro-isobenzofuran-1-yl)-phosphonium; bromide 
• 201230-82-2 carbon monoxide 
• 61592-98-1 1,2-bis(2-bromophenyl)-2-hydroxyethan-1-one 
• 6630-33-7 ortho-bromobenzaldehyde 
• 93097-84-8 di-O-isoamyl-S,S-phthaloyl dixanthate (symmetrical) 
• 93097-83-7 di-O-isobutyl-S,S-phthaloyl dixanthate (symmetrical) 
• 93097-82-6 di-O-isopropyl-S,S-phthaloyl dixanthate (symmetrical) 
• 88-95-9 Phthaloyl dichloride 
• 109-99-9 tetrahydrofuran 
• 93097-87-1 di-O-isoamyl-S,S-phthaloyl dixanthate (unsymmetrical) 
• 93097-86-0 di-O-isobutyl-S,S-phthaloyl dixanthate (unsymmetrical) 
• 93097-85-9 di-O-isopropyl-S,S-phthaloyl dixanthate (unsymmetrical) 
• 601-70-7 3,3-dichlorophthalide 

Downstream Products

• 118-90-1 ortho-methylbenzoic acid 
• 87-41-2 2-benzofuran-1(3H)-one 
• 4281-17-8 2,2'-(ethane-1,2-diyl)bisbenzoic acid 
• 2289-05-6 5,5'-dihydro-5-oxo-diphthalylidene 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 49618-47-5 3-(2-carboxyphenyl)-3,4-dihydroisocoumarin 
• 78229-52-4 <1R-(1α,2β,3α,4β)>-Tetraspiro-3',3'',3''',3''''-tetraon 
• 1657-49-4 1-chloro-4-[(Z)-2-phenylethenyl]benzene 
• 78229-54-6 <1'R-(1'α,2'β,3'β,4'α)>-4'-(4-Chlorphenyl)-3'-phenyldispiro-3,3''-dion 
• 78229-57-9 <1'R-(1'α,2'β,3'α,4'α)>-3'-Chlor-3',4'-diphenyldispiro-3,3''-dion 
• 78229-55-7 <1'R-(1'α,2'β,3'β,4'α)>-3'-Phenyl-4'-(trans-phenylethenyl)dispiro-3,3''-dion 
• 645-49-8 cis-stilben 
• 78229-53-5 <1'R-(1'α,2'β,3'β,4'α)>-3',4'-Diphenyldispiro-3,3''-dion 

Relevant articles and documents

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High-Intensity Laser-Jet Photochemistry: Formation of Benzocyclobutenedione from 1,2,3-Indantrione via Transient Targeting

The photochemistry of 1,2,3-indantrione (1) under high-intensity (laser-jet) conditions has been investigated.Irradiation of trione 1 in a benzene solution under laser-jet conditions produces a complex mixture in which benzocyclobutenedione (2) is observed to be the sole high-intensity product (ca. 11percent yield, six cycles, 3..5 W MLUV argon ion laser) as compared to conventional irradiation (dispersed laser beam, 20 min, 3.5 W MLUV argon ion laser).Under similar conditions, dione 2 was not observed to undergo photolysis in the laser-jet (mass balance ca. 90percent).Additionally, phthalic anhydride, (E)-1,1'-bis-isobenzofuranylidene-3,3'-dione ((E)-4), and 2-benzopyrano-benzopyran-6,12-dione (5) were identified also in both the laser-jet and conventional irradiations of both trione 1 and dione 2.In view of the previously reported product studies, it is proposed that the formation of dione 2 under laser-jet conditions occurs by a photochemical electrocyclization of the intermediary cyclohexadiene-1,2-bisketene (B).The decarbonylation of trione 1 to bisketene B and the electrocyclization of the transient bisketene B to dione 2 constitute an unprecedented sequential multiple-photon transformation of polyketones in solution, which has been uncovered through product studies by using the novel laser-jet technique.

Palladium-Catalyzed Double Carbonylative Cyclization of Benzoins: Synthesis and Photoluminescence of Bis-Ester-Bridged Stilbenes

A palladium-catalyzed double carbonylative cyclization of benzoins has been developed, which realizes the synthesis of bis-ester-bridged stilbenes just in two steps from aldehydes. Thus, the obtained fully fused tetracyclic π-systems have a pyrano[3,2-b]pyran-2,6-dione (PPD) core on their center, showing two reversible reductions at low potentials. In addition, their photoluminescence properties are strikingly affected by the aromatic rings fused to the PPD core; bis-thieno-fused PPDs are found to be excellent fluorophores with quantum yields up to 0.98.

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New coupling reactions of some acyl chlorides with samarium diiodide in the presence of samarium: Carbinols from three acyl units

A mixture of samarium(II) iodide and samarium can induce a coupling reaction of three molecules of alkanoyl halide to give trialkylcarbinols of 2-hydroxy-1,3-diones. When aliphatic, unbranched alkanoyl chlorides are used, this new coupling reaction provides trimeric products as the main reaction products. Tetrahydropyran (THP) proved superior as the solvent because no ring-opening and subsequent reaction with the alkanoyl halides was observed under the reaction conditions, unlike when THF was used. Wiley-VCH Verlag GmbH, 2000.