193607-42-0

Upstream product

• 65926-39-8 (R)-benzyl 2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate 
• 121-45-9 phosphorous acid trimethyl ester 
• 21209-51-8 N-benzyloxycarbonyl-L-serine benzyl ester 
• 16938-05-9 (S)-N-(benzyloxycarbonyl)-O-(p-toluenesulfonyl)serine benzyl ester 

Downstream Products

• 193607-44-2 (R)-2-Benzyloxycarbonylamino-3-(hexadecyloxy-methoxy-phosphoryl)-propionic acid benzyl ester 

Relevant academic research and scientific papers

Alkylphospho-L-serine analogues: Synthesis of cytostatically active alkylphosphono derivatives

Hexadecylphosphono-L-seline (2) was synthesised by phospholipase-D- catalysed transesterification of hexadecylphosphonocholine in the presence of L-serine. The synthesis of β-O-hexadecylphosphono-L-alanine (10) starting from N-benzyloxycarbonyl-L-serine benzyl ester is reported. The compounds 2 and 10 were found to cxhibit cytostatic activity in vitro.