Bioorganic and Medicinal Chemistry Letters p. 1739 - 1742 (1997)
Update date:2022-07-29
Topics:
Brachwitz
Oelke
Bergmann
Langen
Hexadecylphosphono-L-seline (2) was synthesised by phospholipase-D- catalysed transesterification of hexadecylphosphonocholine in the presence of L-serine. The synthesis of β-O-hexadecylphosphono-L-alanine (10) starting from N-benzyloxycarbonyl-L-serine benzyl ester is reported. The compounds 2 and 10 were found to cxhibit cytostatic activity in vitro.
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Doi:10.1016/S0008-6215(97)00122-5
(1997)Doi:10.1021/ja01212a064
(1946)Doi:10.1021/jo970733a
(1997)Doi:10.1039/c8cc03999b
(2018)Doi:10.1021/jo970554t
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(1997)
