19363-99-6

Basic information

• Product Name: 3-Iodopyrazolo[1,5-a]pyridine, 97%
• Synonyms: Pyrazolo[1,5-a]pyridine, 3-iodo-;3-Iodopyrazolo[1,5-a]pyridine, 97%
• CAS NO: 19363-99-6
• Molecular Formula: C7H5IN2
• Molecular Weight: 244.03247
• Mol File: 19363-99-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 67-69℃
• Appearance: Brown/Solid
• Sensitive: Light Sensitive
• CAS DataBase Reference: 3-Iodopyrazolo[1,5-a]pyridine, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iodopyrazolo[1,5-a]pyridine, 97%(19363-99-6)
• EPA Substance Registry System: 3-Iodopyrazolo[1,5-a]pyridine, 97%(19363-99-6)

Safety Data

• Hazardous Substances Data: 19363-99-6(Hazardous Substances Data)

Usage

Uses

Mostly used in the suzuki coupling reaction.

Upstream product

• 16205-46-2 pyrazolo[1,5-a]pyridine-3-carboxylic acid 
• 1207557-48-9 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazolo[1,5-a]pyridine 
• 274-56-6 3-azaindolizine 

Downstream Products

• 1207557-48-9 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazolo[1,5-a]pyridine 
• 274-56-6 3-azaindolizine 
• 1224709-13-0 3-(2,5-dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine 
• 1383675-58-8 C₁₄H₁₀N₄ 
• 1383675-62-4 3-(4-fluorophenyl)pyrazolo[1,5-a]pyridine 
• 1383675-63-5 3-(m-tolyl)pyrazolo[1,5-a]pyridine 
• 1383675-64-6 3-(p-tolyl)pyrazolo[1,5-a]pyridine 
• 1383675-70-4 4-(pyrazolo[1,5-a]pyridin-3-yl)benzonitrile 
• 1383675-71-5 3-(pyrazolo[1,5-a]pyridin-3-yl)benzonitrile 
• 1383675-72-6 3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridine 
• 1383675-75-9 3-phenylpyrazolo[1,5-a]pyridine 
• 1383675-76-0 3-(o-tolyl)pyrazolo[1,5-a]pyridine 
• 1383675-77-1 3-(2-methoxyphenyl)pyrazolo[1,5-a]pyridine 
• 1383675-80-6 3-(3-fluorophenyl)pyrazolo[1,5-a]pyridine 

Relevant articles and documents

INHIBITORS OF CYCLIN-DEPENDENT KINASES

Provided herein are compounds which are inhibitors of cyclin-dependent kinases (CDKs), pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

PHARMACEUTICALS COMPRISING BIARYL DERIVATIVES OR SALTS THEREOF

PROBLEM TO BE SOLVED: To provide compounds with excellent antimycotic activity against Trichophyton. SOLUTION: The invention provides pharmaceuticals comprising biaryl derivatives represented by general formula (I) or salts thereof, where ring A is optionally substituted phenyl or the like; Q is CH2 or the like; X1, X2 and X3 are CR1 or the like; and Y is CH or N. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Optimized scale up of 3-pyrimidinylpyrazolo[1,5-a]pyridine via Suzuki coupling; A general method of accessing a range of 3-(hetero)arylpyrazolo[1,5-a] pyridines

We have developed an improved synthesis of 3-(hetero)aryl pyrazolo[1,5-a]pyridines (such as 3-(2,5-dichloropyrimidin-4-yl)pyrazolo[1,5-a] pyridine (8)) via an optimized synthesis and Suzuki coupling of 3-pyrazolo[1,5-a]pyridine boronic ester 10. These conditions are applicable to both high throughput chemistry and large scale synthesis of these medicinally important compounds. The scope of this chemistry has been further extended to include the synthesis and coupling of a novel boronic ester, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-5H-pyrazolo[5,1-b] [1,3]oxazine (43).