193686-75-8 Usage
Uses
Used in Pharmaceutical Industry:
(R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a potential pharmaceutical compound for its structural similarity to other biologically active molecules, which may lead to the development of new drugs with various therapeutic applications.
Used in Research and Development:
(R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a research tool to study the effects of its enantiomers on biological systems, as the presence of a chiral center suggests that the two enantiomers may have different biological activities. This can contribute to the understanding of stereoselectivity in drug action and the development of more effective and safer medications.
Used in Drug Design and Optimization:
(R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine can be utilized in drug design and optimization processes, as its unique structure may serve as a starting point for the development of novel therapeutic agents with improved pharmacological properties.
Used in Chemical Synthesis:
(R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine may also be used as an intermediate or building block in the synthesis of more complex molecules, potentially leading to the creation of new chemical entities with diverse applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 193686-75-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,6,8 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 193686-75:
(8*1)+(7*9)+(6*3)+(5*6)+(4*8)+(3*6)+(2*7)+(1*5)=188
188 % 10 = 8
So 193686-75-8 is a valid CAS Registry Number.
193686-75-8Relevant academic research and scientific papers
An efficient synthesis of optical isomers of vasopressin V2 receptor antagonist OPC-41061 by lipase-catalyzed enantioselective transesterification
Matsubara, Jun,Morita, Seiji,Yamashita, Hiroshi,Otsubo, Kenji,Kitano, Kazuyoshi,Ohtani, Tadaaki,Kawano, Yoshikazu,Bando, Masahiko,Kido, Masaru,Ochida, Minoru,Tabusa, Fujio
, p. 131 - 138 (2007/10/03)
The optically active enantiomers of 7-chloro-5-hydroxy-1-[2- methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro- 1H- 1-benzazepine (OPC-41061, 1) were enantioselectively synthesized. The chiral acetate ((R)-(-)-3) and the chiral alcohol ((S)-(+)-2) were prepared via the resolution of the racemic alcohol ((±)-2) using the lipase-mediated transesterification with vinyl acetate. Compounds ((R)-(-)-3) and ((S)-(+)-2) were converted to optically active 1.
