193686-74-7 Usage
Uses
Used in Pharmaceutical Industry:
(R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a dopamine receptor agonist for the treatment of neurological and psychiatric disorders such as schizophrenia and Parkinson's disease. Its agonist activity on dopamine receptors can help alleviate symptoms associated with these conditions.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a protecting group for the nitrogen atom during chemical reactions. The tosyl group can be introduced and later removed under mild conditions, thus protecting the nitrogen from unwanted reactions and facilitating the synthesis of more complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 193686-74-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,6,8 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 193686-74:
(8*1)+(7*9)+(6*3)+(5*6)+(4*8)+(3*6)+(2*7)+(1*4)=187
187 % 10 = 7
So 193686-74-7 is a valid CAS Registry Number.
193686-74-7Relevant academic research and scientific papers
An efficient synthesis of optical isomers of vasopressin V2 receptor antagonist OPC-41061 by lipase-catalyzed enantioselective transesterification
Matsubara, Jun,Morita, Seiji,Yamashita, Hiroshi,Otsubo, Kenji,Kitano, Kazuyoshi,Ohtani, Tadaaki,Kawano, Yoshikazu,Bando, Masahiko,Kido, Masaru,Ochida, Minoru,Tabusa, Fujio
, p. 131 - 138 (2007/10/03)
The optically active enantiomers of 7-chloro-5-hydroxy-1-[2- methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro- 1H- 1-benzazepine (OPC-41061, 1) were enantioselectively synthesized. The chiral acetate ((R)-(-)-3) and the chiral alcohol ((S)-(+)-2) were prepared via the resolution of the racemic alcohol ((±)-2) using the lipase-mediated transesterification with vinyl acetate. Compounds ((R)-(-)-3) and ((S)-(+)-2) were converted to optically active 1.
