331947-59-2

Usage

Uses

Used in Organic Chemistry:
(R)-7-chloro-5-methoxymethyloxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as an intermediate for the synthesis of other complex molecules, taking advantage of its unique functional groups and reactivity.
Used in Pharmaceutical Industry:
(R)-7-chloro-5-methoxymethyloxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a potential candidate for drug development due to its complex structure and chiral nature, which may offer novel therapeutic properties and selectivity.
Used in Materials Science:
(R)-7-chloro-5-methoxymethyloxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine is used as a component in the development of new materials, possibly due to its unique structural features and potential for molecular recognition or self-assembly processes.

Upstream product

• 193686-74-7 (R)-5-acetoxy-7-chloro-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 193686-76-9 7-chloro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one 
• 926035-09-8 7-chloro-5-methoxymethoxy-1-(p-toluenesulfonyl)-2,3-dihydro-1H-1-benzazepine 
• 926035-12-3 (4S,5S)-7-chloro-4-hydroxy-5-methoxymethoxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 107-30-2 chloromethyl methyl ether 
• 193686-75-8 (R)-7-chloro-5-hydroxy-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 

Downstream Products

• 331947-63-8 (R)-7-chloro-5-methoxymethyloxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 331947-66-1 (+)-Tolvaptan 

Relevant academic research and scientific papers

Efficient synthesis of optically active 4,5-dihydroxy-2,3,4,5-tetrahydro-IH-1-benzazepine derivatives utilizing lipase-catalyzed transesterification

As an efficient and enantioselective synthesis of the 4,5-dihydroxybenzazepine compounds, the syntheses of optically active 5-0-protected tranAs an efficient and enantioselective synthesis of the 4,5-dihydroxybenzazepine compounds, the syntheses of optica

An efficient synthesis of optical isomers of vasopressin V2 receptor antagonist OPC-41061 by lipase-catalyzed enantioselective transesterification

The optically active enantiomers of 7-chloro-5-hydroxy-1-[2- methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro- 1H- 1-benzazepine (OPC-41061, 1) were enantioselectively synthesized. The chiral acetate ((R)-(-)-3) and the chiral alcohol ((S)-(+)-2) were prepared via the resolution of the racemic alcohol ((±)-2) using the lipase-mediated transesterification with vinyl acetate. Compounds ((R)-(-)-3) and ((S)-(+)-2) were converted to optically active 1.