193693-71-9Relevant academic research and scientific papers
Water-mediated transition-metal-free Tsuji-Trost-type reaction
Chevrin, Carole,Le Bras, Jean,Hénin, Fran?oise,Muzart, Jacques
, p. 8099 - 8102 (2003)
The treatment of 1-acetoxy-1,3-diphenylpropene (1) by C-, O-, S- and N-nucleophiles in basic aqueous media produced the corresponding substitution products in the absence of a transition-metal catalyst. Mechanistic studies, using (S)-1 and p-MeC6/su
Water promoted allylic nucleophilic substitution reactions of (: E)-1,3 diphenylallyl acetate
Ghorpade, Seema A.,Sawant, Dinesh N.,Makki, Arwa,Sekar, Nagaiyan,Eppinger, J?rg
supporting information, p. 425 - 430 (2018/02/07)
A transition metal free, water based, greener protocol for the allylic alkylation, allylic amination, O-allylation of (E)-1,3-diphenylallyl acetate is described. The developed methodology is applicable for a wide range of nucleophiles furnishing excellent yields of corresponding products up to 87% under mild reaction conditions. A distinct effect of water and base is explored for allylic nucleophilic substitution reactions of (E)-1,3-diphenylallyl acetate.
