1938-62-1

Usage

Uses

Used in the Production of Polyurethane Foams and Elastomers:
N,N,N,N-Tetramethyl-1,10-decanediamine is used as a catalyst in the production of polyurethane foams and elastomers, facilitating the control of reaction rates and improving the mechanical properties of the resulting materials.
Used as a Curing Agent for Epoxy Resins:
In the industry of epoxy resins, N,N,N,N-Tetramethyl-1,10-decanediamine serves as a curing agent, which is essential for the hardening and setting of the resin, thereby enhancing its structural integrity and performance.
Used as a Corrosion Inhibitor in Metalworking Fluids:
N,N,N,N-Tetramethyl-1,10-decanediamine is utilized as a corrosion inhibitor in metalworking fluids, helping to prevent the degradation of metal surfaces during manufacturing processes, thus extending the life of the machinery and improving the quality of the final product.
Used in the Synthesis of Pharmaceuticals and Agricultural Chemicals:
N,N,N,N-Tetramethyl-1,10-decanediamine also finds application in the synthesis of various pharmaceuticals and agricultural chemicals, where it contributes to the development of new and effective products for health and agriculture.

Upstream product

• 101098-49-1 N¹,N¹,N¹⁰,N¹⁰-tetramethyldeca-2,8-diyne-1,10-diamine 
• 4101-68-2 1,10-dibromodecane 
• 124-40-3 dimethyl amine 
• 50-00-0 formaldehyd 
• 1938-59-6 N¹,N¹-dimethyldecane-1,10-diamine 
• 646-25-3 diaminodecane 
• 5929-13-5 3-Dimethylamino-propionaldehyde oxime 
• 112-47-0 1,10-Decanediol 
• 553-90-2 Dimethyl oxalate 
• 16851-30-2 β-Dimethylamino-propionaldehyd-diethylacetal 
• 7408-92-6 1,10-diaminodecane dihydrochloride 

Downstream Products

• 105730-92-5 1,10-Bis--decan-dijodid 
• 25344-92-7 C₃₀H₅₈N₂O₄⁽²⁺⁾*2Cl^(1-) 

Relevant academic research and scientific papers

Selective Synthesis of Bisdimethylamine Derivatives from Diols and an Aqueous Solution of Dimethylamine through Iridium-Catalyzed Borrowing Hydrogen Pathway

Bisdimethylamine derivatives are an important class of compounds in the polymer and pharmaceutical industries. However, existing methods for the synthesis of these compounds have several drawbacks such as low selectivity, use of toxic reagents, and generation of waste. In this study, a new system was developed for the selective synthesis of bisdimethylamine derivatives using a diol and dimethylamine as starting materials and an iridium complex bearing an N-heterocyclic carbene ligand as catalyst. The starting materials were easily available, less toxic, inexpensive, and easy to handle. The reaction proceeded efficiently through a borrowing hydrogen pathway under aqueous conditions, without any additional organic solvent, to afford various bisdimethylamine derivatives in good to excellent yields.

QUATERNARY AMINE COMPOUNDS WITH ISOPROPYLMETHYLPHENOL ESTER MOIETIES AS ANTIVIRALS, ANTIBACTERIALS AND ANTIMYCOTICS

Disclosed are compounds having the following formula (I): Formula (I) wherein R is an alkylene chain having between 8 and 20 carbon atoms, and A is one or more anions having a total charge of -2, or R is a quaternary amine having the following formula (Ia

Method for preparing N,N-tetramethyl decamethylene diamine

The invention belongs to the technical field of chemical industry and particularly relates to a method for preparing N,N-tetramethyl decamethylene diamine. The invention provides the method for preparing the N,N-tetramethyl decamethylene diamine. According to the method, the problems of the traditional synthesis process of the N,N-tetramethyl decamethylene diamine that the volume of wastewater islarge, the production cost is high, and the product purity is poor are solved; and the method has the advantages of simplicity in operation, environment-friendliness, high yield and good product purity.

COMPOUNDS AND COMPOSITIONS

Disclosed are compounds having the following formula: (I) wherein R is an alkane chain having between 8 and 20 carbon atoms, and A is one or more anions having a total charge of -2; or R is a quaternary amine having the following formula: (la) wherein Ra

Antibacterial and Antibiofilm Activity of Cationic Small Molecules with Spatial Positioning of Hydrophobicity: An in Vitro and in Vivo Evaluation

More than 80% of the bacterial infections are associated with biofilm formation. To combat infections, amphiphilic small molecules have been developed as promising antibiofilm agents. However, cytotoxicity of such molecules still remains a major problem. Herein we demonstrate a concept in which antibacterial versus cytotoxic activities of cationic small molecules are tuned by spatial positioning of hydrophobic moieties while keeping positive charges constant. Compared to the molecules with more pendent hydrophobicity from positive centers (MIC = 1-4 μg/mL and HC50 = 60-65 μg/mL), molecules with more confined hydrophobicity between two centers show similar antibacterial activity but significantly less toxicity toward human erythrocytes (MIC = 1-4 μg/mL and HC50 = 805-1242 μg/mL). Notably, the optimized molecule is shown to be nontoxic toward human cells (HEK 293) at a concentration at which it eradicates established bacterial biofilms. The molecule is also shown to eradicate preformed bacterial biofilm in vivo in a murine model of superficial skin infection.

A new class of bolaforms bearing sulfobetaine and cationic heads: Synthesis and aggregation properties

We describe here a convenient route to a new family of bolaforms bearing sulfobetaine and cationic heads, which could be scaled up for industrial applications. Their aggregation modes were studied by measurement of surface tension and by dynamic light scattering and transmission electronic microscopy methods. Grafting a hydrophobic chain onto the cationic head modifies both the surface properties and aggregation. Compared to conventional bolaforms, the relationship between the length of the spacer and the side-chain and the resultant hydrophobic interactions are at the origin of these novel properties. Various models of these molecular associations were proposed.

Fast N-methylation of amines under microwave irradiation

Primary and secondary amines are quickly N-methylated by methanal and formic acid under microwave irradiation.