193814-09-4Relevant academic research and scientific papers
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action
Jimonet, Patrick,Bohme, Georg Andrees,Bouquerel, Jean,Boireau, Alain,Damour, Dominique,Debono, Marc Williams,Genevois-Borella, Arielle,Hardy, Jean-Claude,Hubert, Philippe,Manfre, Franco,Nemecek, Patrick,Pratt, Jeremy,Randle, John C.R.,Ribeill, Yves,Stutzmann, Jean-Marie,Vuilhorgne, Marc,Mignani, Serge
, p. 127 - 132 (2007/10/03)
A novel series of 2- and 9-disubstituted heterocyclic-fused 4-oxo-indeno[1,2-e]pyrazin derivatives was synthesized. One of them, the 9-(1H-tetrazol-5-ylmethyl)-4-oxo-5,10-dihydroimidazo[1,2-a]indeno[1,2-e]pyraz in-2-yl phosphonic acid 4i exhibited a stron
