193814-41-4

Upstream product

• 34837-55-3 Phenylselenyl bromide 
• 103233-14-3 (4S,5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)-4-methyldihydrofuran-2(3H)-one 
• 193814-38-9 3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-butyric acid ethyl ester 
• 193814-39-0 4RS,5S-5-Hydroxymethyl-4-methyl-4,5-dihydro-2(3H)-furanon 

Downstream Products

• 106820-49-9 2,3-dideoxy-3-C-methyl-5-O-tert-butyldiphenylsilyl-D-glycero-pent-2-eno-1,4-lactone 
• 106820-52-4 (2R,3R,4S)-5-[(tert-butyldiphenylsilyl)oxy]-2-hydroxy-3-methyl-4-pentanolide 
• 106820-50-2 2,3-dideoxy-3-C-methyl-5-O-tert-butyldiphenylsilyl-D-threo-pentono-1,4-lactone 

Relevant academic research and scientific papers

Synthesis of γ-lactone derivatives as a key intermediate for the spiroketal fragment in calyculin A

A simple and safe route to the D-xylone-l,4-lactone derivative 3, a key intermediate for the synthesis of the spiroketal fragment in calyculin A (I) has been explored without the use of hazardous diazomethane on a large scale.