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3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride, commonly known as pioglitazone hydrochloride, is a hydrochloride salt of the thiazolidinedione derivative. It is a medication primarily used for the treatment of type 2 diabetes, functioning by enhancing the body's sensitivity to insulin, which in turn helps to reduce blood sugar levels.

19382-49-1

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19382-49-1 Usage

Uses

Used in Pharmaceutical Industry:
3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride is used as an antidiabetic medication for the treatment of type 2 diabetes. It is utilized to improve insulin resistance, which is a key factor in the development of the disease. 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride aids in lowering blood sugar levels by increasing the body's sensitivity to insulin, and it is often prescribed in conjunction with other diabetes medications to achieve better control of blood glucose levels.
Additionally, 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride is used as a therapeutic agent for managing dyslipidemia in type 2 diabetes patients. It helps in reducing triglyceride levels and increasing HDL cholesterol levels, contributing to a better lipid profile and overall cardiovascular health.
However, it is important to note that the use of 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride may be accompanied by potential side effects such as weight gain, fluid retention, and an increased risk of heart failure. Therefore, it is crucial for healthcare providers to carefully consider the benefits and risks when prescribing this medication to patients with type 2 diabetes.

Check Digit Verification of cas no

The CAS Registry Mumber 19382-49-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,3,8 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19382-49:
(7*1)+(6*9)+(5*3)+(4*8)+(3*2)+(2*4)+(1*9)=131
131 % 10 = 1
So 19382-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H8N2O2S/c6-1-2-7-4(8)3-10-5(7)9/h1-3,6H2

19382-49-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-aminoethyl)-1,3-thiazolidine-2,4-dione,hydrochloride

1.2 Other means of identification

Product number -
Other names 3-<2-Amino-ethyl>-thiazolidin-2.4-dion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19382-49-1 SDS

19382-49-1Downstream Products

19382-49-1Relevant academic research and scientific papers

New data on the alkylation of cyclic thioureas with α-halocarboxylic acids and their esters. 1. Alkylation of ethylene thiourea

Kushakova,Ramsh,Garabadgiu

, p. 221 - 226 (2006)

The detailed scheme of reactions, occurring on interacting ethylene thiourea with chloroacetic acid and its esters, has been supplemented with a series of new reactions. The whole spectrum of products formed on interaction of ethylene thiourea with 2-bromobutyric acid has been obtained. 2006 Springer Science+Business Media, Inc.

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