19384-12-4

Basic information

• Product Name: Thiourea, N-(5-chloro-2-methylphenyl)-N'-ethyl-
• Synonyms: N-(5-chloro-2-methylphenyl)-N '-ethylthiourea;N-Ethyl-N'-(5-chlor-2-methylphenyl)-thioharnstoff;Thiourea,N-(5-chloro-2-methylphenyl)-N'-ethyl
• CAS NO: 19384-12-4
• Molecular Formula: C10H13ClN2S
• Molecular Weight: 228.74200
• Mol File: 19384-12-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thiourea, N-(5-chloro-2-methylphenyl)-N'-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-(5-chloro-2-methylphenyl)-N'-ethyl-(19384-12-4)
• EPA Substance Registry System: Thiourea, N-(5-chloro-2-methylphenyl)-N'-ethyl-(19384-12-4)

Safety Data

• Hazardous Substances Data: 19384-12-4(Hazardous Substances Data)

Upstream product

• 19241-36-2 5-chloro-2-methylphenylisothiocyanate 
• 75-04-7 ethylamine 

Downstream Products

• 548796-93-6 1-ethyl-3-(5-fluoro-2-methylphenyl)-2-thioxo-4,5-imidazolidinedione 

Relevant articles and documents

Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents

A series of 1-alkyl-3-phenylthiourea analogues were prepared and evaluated as HDL- and Apo A-I-elevating and triglyceride-lowering agents. Several derivatives were superior to gemfibrozil (1). The optimal analogue 8d (HDL376) was shown to raise HDL choles

1,3-Disubstituted-2- thioxo-imidazolidine-4,5-dione derivatives useful in the treatment of atherosclerosis

Antiatherosclerotic compounds of Formula I are provided: wherein: R is lower alkyl, alkenyl, alkynyl, or —O—(CH2)n—COOR′; R′ is lower alkyl; n is an integer of 1-3; Ar is phenyl, or phenyl substituted with one or more of halogen, lower alkyl, alkenyl, alkynyl, alkoxy, perfluoroalkyl, perfluoroalkoxy, or alkylthio; and pharmaceutically acceptable salts thereof.