19241-36-2 Usage
Uses
Used in Organic Synthesis:
5-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE is used as a reagent for the preparation of heterocyclic compounds, which are essential in the development of new organic compounds with potential applications in various industries.
Used in Pharmaceutical Research:
In pharmaceutical research, 5-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE is employed as a reagent for the synthesis of pharmaceutical intermediates. These intermediates are crucial for the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
5-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE is used in the production of agrochemicals, contributing to the development of new pesticides and other agricultural chemicals that can improve crop yield and protect plants from pests and diseases.
Used in Chemical Synthesis as a Building Block:
5-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE is also used as a building block in chemical synthesis, allowing for the creation of more complex molecules with potential applications in various fields, such as materials science and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 19241-36-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,4 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19241-36:
(7*1)+(6*9)+(5*2)+(4*4)+(3*1)+(2*3)+(1*6)=102
102 % 10 = 2
So 19241-36-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClNS/c1-6-2-3-7(9)4-8(6)10-5-11/h2-4H,1H3
19241-36-2Relevant academic research and scientific papers
NaOH-promoted one-pot aryl isothiocyanate synthesis under mild benchtop conditions
Li, Hang,Liu, Xinyun,Yin, Xiaogang
supporting information, p. 839 - 844 (2021/05/27)
In this work, we have established a green synthesis of aryl isothiocyanates promoted by the low-cost and readily available NaOH from aryl amines and carbon disulfide in a one-pot procedure. The developed protocol features no extra desulfurating reagents and mild benchtop conditions, in which NaOH serves as both the base and the desulfurating reagent to decompose the dithiocarbamate intermediate. Fourteen examples of aryl amines bearing electronic neutral, rich and poor substituents, as well as benzylamine, have proved to be compatible substrates in the developed method to furnish the corresponding isothiocyanates. The reaction has been performed on a gram scale to further demonstrate its synthetic utility. Compared to the reported base-promoted synthesis of aryl isothiocyanates that requires the use of special equipment, such as the ball mill or the microwave reactor, the simplicity in operation and scalability enables this method to efficiently access a variety of aryl isothiocyanates.
