193885-60-8 Usage
General Description
Hexadecanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-, also known as S-palmitoyl fluorenylmethyloxycarbonyl-amino acid or Fmoc-S-palmitoyl, is a chemical compound commonly used in peptide synthesis and solid-phase peptide synthesis (SPPS). It is a derivative of hexadecanoic acid, also known as palmitic acid, and is often used as a protective group for amino acids during peptide synthesis. The Fmoc group is commonly used to provide stability and protection to peptides during the synthesis process. Hexadecanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)- is an important tool in the field of peptide chemistry and plays a crucial role in the development of peptide-based drugs and biomedical research.
Check Digit Verification of cas no
The CAS Registry Mumber 193885-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,8,8 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 193885-60:
(8*1)+(7*9)+(6*3)+(5*8)+(4*8)+(3*5)+(2*6)+(1*0)=188
188 % 10 = 8
So 193885-60-8 is a valid CAS Registry Number.
193885-60-8Relevant articles and documents
Diastereoselective alkylation of schiff bases for the synthesis of lipidic unnatural Fmoc-protected α-amino acids
Papini, Anna Maria,Nardi, Elena,Nuti, Francesca,Uziel, Jacques,Ginanneschi, Mauro,Chelli, Mario,Brandi, Alberto
, p. 2736 - 2741 (2007/10/03)
Peptides with increased lipophilicity can cross cell membranes more easily and have longer half -life times. For these reasons, the synthesis of enantiomerically pure Fmoc-protected lipidic α-amino acids is a relevant goal. Schiff bases originating from the reaction between the two enantiomers of 2-hydroxypinan-3-one with Gly-OtBu were alkylated with a series of long alkyl halides. Diastereomeric excesses were determined by reversed-phase HPLC, under conditions carefully chosen for such lipophilic substrates. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
