193980-01-7

Upstream product

• 193979-98-5 (2R,3S)-3-Ethyl-2-methyl-1-(toluene-4-sulfonyl)-aziridine-2-carboxylic acid methyl ester 
• 193979-97-4 (2R,3S)-3-Ethyl-2-methyl-1-((S)-toluene-4-sulfinyl)-aziridine-2-carboxylic acid methyl ester 
• 193979-96-3 (S)-4-methyl-benzenesulfinic acid propylideneamide 
• 193979-99-6 (2R,3S)-(-)-2-methyl-N-(p-toluenesulfonyl)-3-aminopentanol 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 

Relevant academic research and scientific papers

Aziridine 2-carboxylate ester mediated asymmetric synthesis of α-alkyl β-amino acids

The highly stereoselective ring opening of N-tosylaziridine 2-carboxylate esters with LiAIH4 followed by oxidation of the ensuing syn alcohols results in a highly efficient 4 step asymmetric synthesis of α-methyl β-amino acids from N-sulfinylaziridine 2-carboxylate esters.