19402-33-6

Usage

Molecular Weight

350.52 g/mol
The molecular weight of the compound is 350.52 g/mol, which is the sum of the atomic weights of all the atoms in the molecule.

Classification

Carboxylic Acid
The compound is classified as a carboxylic acid due to the presence of a carboxyl functional group (-COOH).

Core Structure

Phenanthrene Backbone
The core structure of the compound is based on a phenanthrene backbone, which is a tricyclic aromatic hydrocarbon consisting of three fused six-membered rings.

Dodecahydro Ring System

1,4a-Dimethyl-7-(1-methylethylidene)
The compound features a dodecahydro (12-hydrogen) ring system, with a 1,4a-dimethyl and 7-(1-methylethylidene) substituents.

Stereochemistry

(1R, 4aS, 10aR)
The compound has a specific stereochemistry, with the chiral centers labeled as (1R, 4aS, 10aR), indicating the spatial arrangement of the atoms in the molecule.

Applications

Pharmaceuticals, Organic Synthesis, Laboratory Research

Structural Complexity

Intriguing Subject for Study and Exploration
The complex and specific structure of the compound makes it an intriguing subject for further study and exploration in the fields of chemistry and material science.

Upstream product

• 19402-34-7 methyl abieta-8,13⁽¹⁵⁾-dien-18-oate 
• 141-52-6 sodium ethanolate 
• 22628-82-6 8.15-dibromo-8ξ.13ξH-abietanoic acid-(18) 
• 514-10-3 abietic acid 

Downstream Products

• 19402-34-7 methyl abieta-8,13⁽¹⁵⁾-dien-18-oate 
• 185379-95-7 (1R,4aS,10aR)-1,4a-Dimethyl-7-triphenylsilanyloxy-1,2,3,4,4a,5,6,9,10,10a-decahydro-phenanthrene-1-carboxylic acid methyl ester 
• 185379-98-0 (1R,4aS,10aR)-1,4a-Dimethyl-7-(2,2,2-triphenyl-acetoxy)-1,2,3,4,4a,5,6,9,10,10a-decahydro-phenanthrene-1-carboxylic acid methyl ester 
• 65894-41-9 abieta-8,11,13-triene-15,18-diol 

Relevant academic research and scientific papers

Preparation method of 15-hydroxyl dehydrogenated abietane and intermediate of 15-hydroxyl dehydrogenated abietane

The invention discloses a preparation method of 15-hydroxyl dehydrogenated abietane and an intermediate of 15-hydroxyl dehydrogenated abietane. The preparation method comprises the following steps: converting a compound 1 into a compound 5, and converting the compound 5 into a compound 8. According to the method for preparing the compound 8, the problem that a product cannot be separated out of a glacial acetic acid solution because reaction impurities are remarkably increased when the feeding quantity is increased at the hydrogen bromide addition step in the existing synthesis route is solved through continuous screening of a process route. Furthermore, the method provided by the invention is high in yield at each step, easy to amplify and suitable for industrialized large-scale production. (The formula is as shown in the description.).

8. 11, 13 - Lohans Pinaceae - 13 - ol and intermediate preparation method (by machine translation)

The present invention discloses a process for preparing compound 9 shown 8, 11, 13 - Lohans Pinaceae - 13 - alcohol, or its pharmaceutically acceptable salt, or its solvate of the method, the method comprises the following steps: h, in the presence of oxidizing agent and acid, in order to compound 8 as raw material preparation to obtain compound 9; wherein oxidizing agent selected from hydrogen peroxide or over-tertiary butyl alcohol, acid selected from H2 SO4 , Toluenesulfonates. Process for making a compound of the present invention 9 of the method, the method is simple, high yield, easy to enlarge, and is suitable for industrial large-scale production. (by machine translation)

Synthesis and biological evaluation of abietic acid derivatives

A series of C18-oxygenated derivatives of abietic acid were synthesized and evaluated for their cytotoxic, antimycotic, and antiviral activities. In general, the introduction of an aldehyde group at C18 did improve the resultant bioactivity, while the presence of an acid or alcohol led to less active compounds.