Abieta-8,13(15)-diene-18-oic acid methyl ester

Base Information

• Chemical Name: Abieta-8,13(15)-diene-18-oic acid methyl ester
• CAS No.: 19402-34-7
• Molecular Formula: C21H32O2
• Molecular Weight: 316.48
• Mol file: 19402-34-7.mol

Synonyms:[1R,(+)]-1,2,3,4,4a,5,6,7,8,9,10,10aα-Dodecahydro-1,4aβ-dimethyl-7-(1-methylethylidene)-1α-phenanthrenecarboxylic acid methyl ester;Abieta-8,13(15)-diene-18-oic acid methyl ester

Chemical Property of Abieta-8,13(15)-diene-18-oic acid methyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 5.58280

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Abieta-8,13(15)-diene-18-oic acid methyl ester

There total 7 articles about Abieta-8,13(15)-diene-18-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

abieta-8,13(15)-dien-18-oic acid (19402-33-6) + methyl iodide (74-88-4) → methyl abieta-8,13(15)-dien-18-oate (19402-34-7)

Guidance literature:

In acetone; for 12h; Heating;

DOI:10.1016/j.tetlet.2006.02.037

Reference yield: 74.0%

methyl 8,15-dibromoabietan-18-oate (22628-83-7) → methyl abieta-8,13(15)-dien-18-oate (19402-34-7)

Guidance literature:

With lithium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 3.5h;

Reference yield: 56.0%

methyl abietate (127-25-3) → methyl abieta-8,13(15)-dien-18-oate (19402-34-7)

Guidance literature:

methyl abietate; With hydrogen bromide; In acetic acid; for 20h;

With lithium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 16h; Heating;

DOI:10.1016/j.ejmech.2009.01.014

upstream raw materials:

methyl 8,15-dibromoabietan-18-oate

diazomethane

abieta-8,13⁽¹⁵⁾-dien-18-oic acid

methyl iodide

Downstream raw materials:

abieta-8,13⁽¹⁵⁾-dien-18-oic acid

abieta-8,11,13-triene-15,18-diol

13-oxo-13-deisopropyl-abiet-8⁽¹⁴⁾en-15-oic acid

15-hydroxyabietic acid