194099-76-8Relevant academic research and scientific papers
A new multicomponent synthesis of 1,2,3,4-tetrahydroquinolines
Annunziata, Rita,Cinquini, Mauro,Cozzi, Franco,Molteni, Valintina,Schupp, Olaf
, p. 9715 - 9726 (1997)
The synthesis of a variety of differently substituted 1,2,3,4- tetrahydroquinolines by a new three-component reaction involving an imine (Ar-N=CHR), an α-branched and enolizable aldehyde (R1R2CHCHO), and a nucleophile (ROH, ArSH, ArN
Synthesis and characterization of [1]benzopyrano[4,3-d][1,3]benzooxazocin- 13-one and its derivatives
Wang, Jen-Fei,Liao, Yuan-Xiu,Kuo, Pei-Yu,Gau, Yung-Her,Yang, Ding-Yah
, p. 2791 - 2794 (2008/02/11)
This work describes the efficient synthesis of functionalized cleft molecules 6, 6a, 16, 16a, 17, 19 and 20 derived from benzopyrano[4,3-d][1,3] benzooxazocin-13-one. X-ray crystal structure analysis of compounds 6a and 16a revealed that the cleft angles of the planes of the benzopyran moiety and the p-methoxybenzene ring are 109.4° and 108.6°, respectively. The conformation of the aromatic ring at the bridgehead of 16, 16a and 20 is restricted by the gem-dimethyl groups on the C-9 position and the methyl group on the nitrogen atom in the ring. Georg Thieme Verlag Stuttgart.
