194163-31-0 Usage
Description
6-CYANO-1H-INDAZOLE-3-CARBOXYLIC ACID is a chemical compound characterized by the molecular formula C10H6N4O2. It is a white to off-white crystalline solid that holds significant potential in various scientific and industrial applications, particularly in the pharmaceutical sector. Known for its potential biological activities, this compound has been extensively studied for its role in the synthesis of pharmaceutical drugs and indazole derivatives with antimicrobial, antifungal, and anticancer properties. Furthermore, its applications extend to materials science, where it is being investigated for its utility in the development of organic semiconductors and optoelectronic devices.
Uses
Used in Pharmaceutical Industry:
6-CYANO-1H-INDAZOLE-3-CARBOXYLIC ACID is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical structure allows for the development of new drugs with diverse therapeutic applications.
Used in Synthesis of Indazole Derivatives:
In the field of medicinal chemistry, 6-CYANO-1H-INDAZOLE-3-CARBOXYLIC ACID is utilized as a precursor for the synthesis of indazole derivatives. These derivatives exhibit a range of biological activities, including antimicrobial, antifungal, and anticancer properties, making them valuable for the development of new therapeutic agents.
Used in Materials Science:
6-CYANO-1H-INDAZOLE-3-CARBOXYLIC ACID is also used in the field of materials science, particularly for the development of organic semiconductors and optoelectronic devices. Its unique electronic properties and structural characteristics make it a promising candidate for these applications, contributing to advancements in technology and electronics.
Check Digit Verification of cas no
The CAS Registry Mumber 194163-31-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,1,6 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 194163-31:
(8*1)+(7*9)+(6*4)+(5*1)+(4*6)+(3*3)+(2*3)+(1*1)=140
140 % 10 = 0
So 194163-31-0 is a valid CAS Registry Number.
194163-31-0Relevant articles and documents
Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
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Page/Page column 76, (2010/11/26)
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists
Sall, Daniel J.,Arfsten, Ann E.,Bastian, Jolie A.,Denney, Michael L.,Harms, Cathy S.,McCowan, Jefferson R.,Morin Jr., John M.,Rose, Jack W.,Scarborough, Robert M.,Smyth, Mark S.,Um, Suzane L.,Utterback, Barbara G.,Vasileff, Robert T.,Wikel, James H.,Wyss, Virginia L.,Jakubowski, Joseph A.
, p. 2843 - 2857 (2007/10/03)
The use of 5,6-bicyclic amidines as arginine surrogates in the design of a novel class of potent platelet glycoprotein IIb-IIIa receptor (GPIIb-IIIa) antagonists is described. The additional conformational restriction offered by the bicyclic nucleus results in 20-400-fold increases in potency compared to the freely flexible, acyclic benzamidine counterpart. The design, synthesis, structure-activity relationships (SAR), and in vitro activity of this novel class of GPIIb-IIIa antagonists are presented.
