19432-61-2 Usage
General Description
1-benzyl-4-cyano-1,4-dihydropyridine-3-carboxamide is a chemical compound with the molecular formula C17H16N4O. It is a dihydropyridine derivative with a benzyl group and a cyano group attached to the pyridine ring. 1-benzyl-4-cyano-1,4-dihydropyridine-3-carboxamide has been studied for its potential use in the treatment of cardiovascular diseases, specifically hypertension and angina. It is believed to work by blocking calcium channels in smooth muscle cells, causing vasodilation and lowering blood pressure. Additionally, its chemical structure suggests potential for use in medicinal chemistry, particularly for the development of calcium channel blockers and other pharmaceuticals targeting cardiovascular conditions. Further research is needed to fully understand the therapeutic potential and safety profile of 1-benzyl-4-cyano-1,4-dihydropyridine-3-carboxamide.
Check Digit Verification of cas no
The CAS Registry Mumber 19432-61-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,3 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19432-61:
(7*1)+(6*9)+(5*4)+(4*3)+(3*2)+(2*6)+(1*1)=112
112 % 10 = 2
So 19432-61-2 is a valid CAS Registry Number.
19432-61-2Relevant articles and documents
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Foster,Fyfe
, p. 1489 (1969)
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SUBSTITUENT EFFECT IN ADDITION OF CYANIDE ION TO p-SUBSTITUTED 1-BENZYL-3-CARBAMOYLPYRIDINIUM CHLORIDES
Pavlikova-Raclova, Frantiska,Kuthan, Josef
, p. 1401 - 1407 (2007/10/02)
The rate constants k2 and equilibrium constants K=k2/k-2 of the title process (A) have been measured in aqueous solutions of eight quaternary salts of nicotinamide I (R= p-XC6H4CH2) at 298 K.The substituent effects of X= CH3O, CH3, H, F, Cl, COOCH3, CN, and NO2 exhibiting the Hammett dependence have been correlated with half-wave potentials of reduction of the depolarizers I, and the correlation results have been discussed with respect to mechanism of the reaction (A).