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1-benzyl-4-cyano-1,4-dihydropyridine-3-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

19432-61-2

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19432-61-2 Usage

Chemical class

Dihydropyridine derivative

Substituents

Benzyl group, cyano group

Attachment location

Pyridine ring

Potential use

Treatment of cardiovascular diseases (hypertension, angina)

Mechanism of action

Blocking calcium channels in smooth muscle cells

Effect

Vasodilation, lowering blood pressure

Implication

Possible development of calcium channel blockers and other pharmaceuticals targeting cardiovascular conditions

Research status

Further research needed to understand therapeutic potential and safety profile

Check Digit Verification of cas no

The CAS Registry Mumber 19432-61-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,3 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19432-61:
(7*1)+(6*9)+(5*4)+(4*3)+(3*2)+(2*6)+(1*1)=112
112 % 10 = 2
So 19432-61-2 is a valid CAS Registry Number.

19432-61-2Relevant academic research and scientific papers

Addition of Cyanide Ion to Nicotinamide Cations in Acetonitrile. Formation of Non-productive Charge-transfer Complexes

Engbersen, Johan F. J.,Koudijs, Arie,Sleiderink, Hedwig M.,Franssen, Maurice C. R.

, p. 79 - 83 (2007/10/02)

The mixing of equal volumes of 0.2 mmol dm-3 1-benzylnicotinamide ion and 2 mmol dm-3 cyanide ion results in the immediate formation of a transient absorption band at 375 nm which can be ascribed to a charge-transfer complex.This com

SUBSTITUENT EFFECT IN ADDITION OF CYANIDE ION TO p-SUBSTITUTED 1-BENZYL-3-CARBAMOYLPYRIDINIUM CHLORIDES

Pavlikova-Raclova, Frantiska,Kuthan, Josef

, p. 1401 - 1407 (2007/10/02)

The rate constants k2 and equilibrium constants K=k2/k-2 of the title process (A) have been measured in aqueous solutions of eight quaternary salts of nicotinamide I (R= p-XC6H4CH2) at 298 K.The substituent effects of X= CH3O, CH3, H, F, Cl, COOCH3, CN, and NO2 exhibiting the Hammett dependence have been correlated with half-wave potentials of reduction of the depolarizers I, and the correlation results have been discussed with respect to mechanism of the reaction (A).

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