194654-68-7

Upstream product

• 104-84-7 para-methylbenzylamine 
• 933-88-0 ortho-toluoyl chloride 

Downstream Products

• 1026846-57-0 2-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-N-(4-methyl-benzyl)-benzamide 
• 1026913-23-4 2-[2-(3-chloro-phenyl)-2-oxo-ethyl]-N-(4-methyl-benzyl)-benzamide 
• 1026014-94-7 2-[2-(4-chloro-phenyl)-2-oxo-ethyl]-N-(4-methyl-benzyl)-benzamide 

Relevant academic research and scientific papers

ISOQUINOLINONE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS

This invention is directed to isoquinolinone derivatives and their use in modulating the activity of orphan nuclear receptors, pharmaceutical compositions containing such derivatives, and methods of using such derivatives in treating disease-states associ

The preparation of substituted 1(2H)-isoquinolinones from dilithiated 2- methyl-N-arylbenzamides, 2-methyl-N-(arylmethyl)-benzamides, or 2- methylbenzoic acid, 2,2-dimethylhydrazide

2-Methyl-N-arylbenzamides (N-aryl-ortho-toluamides), 2-methyl-N- (arylmethyl)-benzamides (substituted benzyl, N-benzyl-ortho-toluamides), or 2-methylbenzoic acid, 2,2-dimethylhydrazide (ortho-toluic acid, N,N- dimethylhydrazide), were dilithiated with exc