194721-60-3

Upstream product

• 108-05-4 vinyl acetate 
• 117538-45-1 2-bromo-1-(3-chlorophenyl)ethanol 
• 187409-10-5 3-chloro-α,β-dibromoethylbenzene 

Downstream Products

• 20697-04-5 (R)-meta-chlorostyrene oxide 

Relevant academic research and scientific papers

A practical synthesis of (R)-3-chlorostyrene oxide starting from 3- chloroethylbenzene

A novel and practical synthesis of (R)-3-chlorostyrene oxide (-)-1 was achieved starting from commercially available 3-chloroethylbenzene 3. Enantiopure (-)-3-chlorostyrene bromohydrin (-)-5 was obtained by the treatment of racemic (±)-5 with lipase QL in the presence of acylating reagents. 3-Chloro-α,β-dibromoethylbenzene 4, a precursor of (±)-5, was synthesized via the expeditious bromination of 3 which was developed by these authors.