63468-83-7

Usage

Uses

Used in Organic Synthesis:
8-Methoxyjulolidine, 95% is used as a building block for the synthesis of various organic compounds. Its unique chemical structure allows for versatile reactions and the creation of a wide range of molecules, making it a valuable component in the development of new chemical entities.
Used in Material Science:
8-Methoxyjulolidine, 95% is used in the development of advanced materials such as liquid crystals and organic semiconductors. Its properties contribute to the enhancement of material performance, enabling the creation of innovative products with improved characteristics in various applications.
Used in Research and Industrial Applications:
8-Methoxyjulolidine, 95% is utilized in a variety of research and industrial applications due to its unique chemical structure and versatility. It serves as a key component in the exploration of new chemical reactions and the development of novel materials with potential applications in various industries.

Upstream product

• 536-90-3 m-Anisidine 
• 142-28-9 1,3-Dichloropropane 
• 109-64-8 1,3-dibromo-propane 
• 41175-50-2 8-hydroxyjulolidine 
• 77-78-1 dimethyl sulfate 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 41175-50-2 8-hydroxyjulolidine 
• 1061330-74-2 C₂₁H₂₀N₂O₂S 
• 1061330-76-4 C₂₁H₂₃NO₂ 
• 1061330-83-3 C₂₀H₂₀N₂O₄ 
• 55804-67-6 10-acetyl-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinoline-11(5H)-one 
• 194785-18-7 6-carboxy-X-rhodamine 
• 107408-81-1 coumarin 343 methyl ester 
• 55804-65-4 coumarin-343 
• 63149-33-7 9-formyl-8-hydroxyjulolidine 

Relevant academic research and scientific papers

Method for synthesizing 8-hydroxyjulolidine

The invention relates to a method for synthesizing 8-hydroxyjulolidine. The method comprises the following steps: reacting 3-methoxyaniline, X-(CH2)3-Y and an inorganic base under a heating condition,separating water during the reaction, and carrying out post-treatment after the completion of the reaction to obtain crude 8-hydroxyjulolidine; mixing the crude 8-hydroxyjulolidine with a halogen acid, heating the obtained mixture to react the mixture, and cooling and filtering the obtained solution after the reaction is completed in order to obtain a halogen acid salt of 8-hydroxyjulolidine; andmixing the halogen acid salt of 8-hydroxyjulolidine with water, neutralizing the obtained solution with a base, and carrying out extraction, drying, reduced pressure concentrating, beating and purification to obtain the 8-hydroxyjulolidine. The method has the advantages of abandoning of traditional column chromatography purification, suitableness for industrial production, and high yield.

Compounds and Method for Imaging Cancer

A compound, a method of imaging a cell, and a method of detecting a cancer, an inflammatory disease, or a neoplastic disease are provided. The compound includes a nitroxide derivative of a fluorophore that is activatable upon exposure to free radicals. The method of imaging a cell includes contacting the cell with an activatable nitroxide derivative of a fluorophore. The method of detecting a cancer, an inflammatory disease, or a neoplastic disease includes administering an activatable nitroxide derivative of a fluorophore and then imaging one or more cells contacted with the compound.

Novel Iminocoumarin Derivatives: Synthesis, Spectroscopic and Computational Studies

Three novel iminocoumarin derivatives with high quantum yield are synthesized from 3-benzimidazole substituted coumarin and different aromatic aldehydes. The photophysical behavior of the synthesized compounds was studied using UV-visible and fluorescence spectroscopy in polar and non-polar solvents. The compounds show absorption maxima at around 450 nm and emission maxima at around 500 nm. The quantum yields of compounds in dichloromethane and chloroform are more than 0.90. The absorption, emission and quantum yield of compounds are dependent on the polarity of solvents. Along with an intense absorption, these compounds show shoulder absorption peak in the studied solvents. The solvent polarity plots revealed the charge transfer process in the synthesized molecules from donor to acceptor. Density Functional Theory and Time Dependent Density Functional Theory computations have been used to have more understanding of the structural, molecular, electronic and photophysical parameters of the dyes. The dyes were characterized by FT-IR, 1H NMR, 13C NMR and mass spectral analysis.

Extensive reduction in back electron transfer in twisted intramolecular charge-transfer (TICT) coumarin-dye-sensitized TiO2 nanoparticles/film: A femtosecond transient absorption study

We report the synthesis, characterization, and optical and electrochemical properties of two structurally similar coumarin dyes (C1 and C2). These dyes have been deployed as sensitizers in TiO2 nanoparticles and thin films, and the effect of molecular structure on interfacial electron-transfer dynamics has been studied. Steady-state optical absorption, emission, and time-resolved emission studies on both C1 and C2, varying the polarity of the solvent and the solution pH, suggest that both photoexcited dyes exist in a locally excited (LE) state in solvents of low polarity. In highly polar solvents, however, C1 exists in an intramolecular charge-transfer (ICT) state, whereas C2 exists in both ICT and twisted intramolecular charge-transfer (TICT) states, their populations depending on the degree of polarity of the solvent and the pH of the solution. We have employed femtosecond transient absorption spectroscopy to monitor the charge-transfer dynamics in C1- and C2-sensitized TiO2 nanoparticles and thin films. Electron injection has been confirmed by direct detection of electrons in the conduction band of TiO 2 nanoparticles and of radical cations of the dyes in the visible and near-IR regions of the transient absorption spectra. Electron injection in both the C1/TiO2 and C2/TiO2 systems has been found to be pulse-width limited (2 system than in the C1/TiO2 system. The involvement of TICT states in C2 is solely responsible for the higher electron injection yield as well as the slower BET process compared to those in the C1/TiO2 system. Further pH-dependent experiments on C1- and C2-sensitized TiO2 thin films have corroborated the participation of the TICT state in the slower BET process in the C2/TiO2 system.

Development of an ICT-based ratiometric fluorescent hypochlorite probe suitable for living cell imaging

We have judiciously constructed a novel ICT-based ratiometric OCl - probe capable of ratiometric imaging in the live cells based on the new OCl--promoted de-diaminomaleonitrile reaction. The Royal Society of Chemistry 2011.

Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties

We have demonstrated the synthesis of regioisomerically pure unsymmetrical xanthene derivatives consisting of three units which can be independently modified to control their physical properties. The photochemical properties of the synthetic unsymmetrical xanthene derivatives were investigated in solution by UV-vis absorption and fluorescence measurements, and their cell imaging properties were examined by confocal laser-scanning microscopy.

Chemiluminescence of Organic Peroxides: Intramolecular Electron-Exchange Luminescence from a Secondary Perester

The reaction of an aminocoumarincarboxylic acid chloride (Coumarin 343) with 1-phenethyl hydroperoxide results in light emission that is easily detected with the unaided eye.This reaction proceeds through a secondary perester intermediate.Intramolecular electron exchange, modeled after the analogous process in the bioluminescence of the firefly, is proposed as the mechanism for light generation.Attempts to carry out this reaction under conditions where the coumarin acid is recycled were not successful.

Synthesis of Julolidines from Anilines

Substituted julolidines were prepared by a single step of reactions from substituted anilines.