3096-69-3

Basic information

• Product Name: 4-AMINO-2,3-XYLENOL
• Synonyms: 4-AMINO-2,3-XYLENOL;2,3-DIMETHYL-4-AMINOPHENOL;4-amino-2,3-dimethylphenol;4-hydroxy-2,3-dimethylaniline;4-AMINO-2,3-XYLENOL 97+%;4-azanyl-2,3-dimethyl-phenol;4-Amino-2,3-dimethylphenol 4-Hydroxy-2,3-dimethylaniline
• CAS NO: 3096-69-3
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• EINECS: 221-446-4
• Mol File: 3096-69-3.mol
• Article Data: 18

Chemical Properties

• Melting Point: 174°C
• Boiling Point: 296.3 °C at 760 mmHg
• Flash Point: 133 °C
• Appearance: /
• Density: 1.118 g/cm³
• Vapor Pressure: 0.00082mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4-AMINO-2,3-XYLENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-2,3-XYLENOL(3096-69-3)
• EPA Substance Registry System: 4-AMINO-2,3-XYLENOL(3096-69-3)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 3096-69-3(Hazardous Substances Data)

Usage

General Description

4-AMINO-2,3-XYLENOL, also known as 2,3-Dihydroxy-4-methoxyaniline, is a chemical compound commonly used in the production of hair dyes and hair care products. It is a phenol derivative with a molecular formula of C8H11NO2 and is primarily used as a colorant in the cosmetic industry. 4-AMINO-2,3-XYLENOL is known for its ability to impart rich, vibrant color to hair while also providing conditioning and nourishing benefits. However, it is important to note that 4-AMINO-2,3-XYLENOL should be used with caution as it can cause allergic reactions in some individuals and is classified as a skin sensitizing agent. Therefore, it is important to follow proper safety guidelines when handling and using products containing 4-AMINO-2,3-XYLENOL.

InChI:InChI=1/C8H11NO/c1-5-6(2)8(10)4-3-7(5)9/h3-4,10H,9H2,1-2H3

Upstream product

• 74783-54-3 1-hydroxy-2,3-dimethyl-4-nitrosobenzene 
• 19499-93-5 2,3-dimethyl-4-nitrophenol 
• 526-75-0 2,3-Dimethylphenol 
• 78660-13-6 p-(2,3-dimethyl-4-hydroxyphenylazo)benzenesulphonic acid 
• 3096-62-6 N-(2,3-dimethylphenyl)hydroxylamine 
• 83-41-0 2,3-dimethylnitrobenzene 
• 57597-99-6 2,3-Dimethyl-4-phenylazo-phenol 
• 305-80-6 4-diazobenzenesulfonic acid 
• 64-17-5 ethanol 

Downstream Products

• 526-86-3 2,3-dimethyl-1,4-benzoquinone 
• 2011-57-6 N-(4-hydroxy-2,3-dimethyl-phenyl)acetamide 
• 321949-08-0 N-(4-hydroxy-2,3-dimethylphenyl)benzamide 
• 312519-92-9 N-(4-hydroxy-2,3-dimethylphenyl)-4-methylbenzamide 
• 224450-47-9 (4-hydroxy-2,3-dimethylphenyl)carbamic acid tert-butyl ester 
• 1616410-88-8 N-(4-hydroxy-2,3-dimethylphenyl)-N′-(4-chlorophenylsulfonyl)acetamidine 
• 1616410-88-8 N-(4-hydroxy-2,3-dimethylphenyl)-N′-(4-chlorophenylsulfonyl)acetamidine 
• 1413925-86-6 N-(2,3-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)-3-phenylprop-2-enamide 
• 1413925-71-9 (2E)-N-(4-hydroxy-2,3-dimethylphenyl)-3-phenylprop-2-enamide 
• 1413925-81-1 N-(2,3-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)phenoxyacetamide 
• 1413925-63-9 N-(4-hydroxy-2,3-dimethylphenyl)-2-phenoxyacetamide 
• 1413925-76-4 N-(2,3-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)-4-methylphenylacetamide 
• 1413925-55-9 N-(4-hydroxy-2,3-dimethylphenyl)-2-(4-methylphenyl)acetamide 
• 321941-34-8 N-(2,3-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)phenylacetamide 

Relevant articles and documents

Novel potent BRAF inhibitors: Toward 1 nM compounds through optimization of the central phenyl ring

BRAF, a serine/threonine specific protein kinase that is part of the MAPK pathway and acts as a downstream effector of RAS, is a potential therapeutic target in melanoma. We have developed a series of small-molecule BRAF inhibitors based on a 1H-imidazo[4,5-b]pyridine-2(3H)-one scaffold (ring A) as the hinge binding moiety and a number of substituted phenyl rings C that interact with the allosteric binding site. The introduction of various groups on the central phenyl ring B combined with appropriate A- and C-ring modifications afford very potent compounds that inhibit V600EBRAF kinase activity in vitro and oncogenic BRAF signaling in melanoma cells. Substitution on the central phenyl ring of a 3-fluoro, a naphthyl, or a 3-thiomethyl group improves activity to yield compounds with an IC50 of 1 nM for purified V 600EBRAF and nanomolar activity in cells.

One step hair coloring compositions using salts

A hair coloring composition comprising the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an amino phenol, a naphthol, a polyhydric phenol, a catechol and mixtures thereof; wherein the composition comprising one or more oxidative hair coloring agents further comprises al least one water soluble carbonate releasing salts; and optionally a water soluble ammonium salt, is described.

Hair conditioning compositions and their use in hair colouring compositions

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