195073-77-9

Upstream product

• 89-61-2 2,5-dichloronitrobenzene 
• 108-98-5 thiophenol 
• 4235-20-5 5-chloro-2-phenylsulfanyl-aniline 
• 4548-56-5 4-chloro-2-nitrophenyl phenyl sulfide 
• 195073-72-4 2-Bromo-N-(5-chloro-2-phenylsulfanyl-phenyl)-acetamide 

Relevant academic research and scientific papers

New spermine and spermidine derivatives as potent inhibitors of trypanosoma cruzi trypanothione reductase

Several spermine and spermidine derivatives containing 2-amino diphenylsulfide substituents were prepared and tested for their inhibiting effects on Trypanosoma cruzi trypanothione reductase. IC50 values were assessed between 0.3 and 3 μM. Compound 32 (K(i) = 0.4 μM) is the most potent TR inhibitor described so far.