1951408-58-4 Usage
Uses
Used in Pharmaceutical Industry:
MAK-683 is used as an intermediate for the preparation of triazolopyrimidine compounds, which are beneficial in the treatment of diseases or disorders mediated by EED and/or PRC2. Its potent inhibition of H3K27 trimethylation makes it a valuable compound in the development of therapeutics targeting these pathways.
Used in Cancer Research:
MAK-683 is used as an EED inhibitor, playing a crucial role in the study and treatment of various types of cancer. Its ability to inhibit the proliferation of B cell lymphoma cells highlights its potential as a therapeutic agent in oncology.
Used in Drug Development:
MAK-683 serves as a key component in the development of novel drug delivery systems and therapeutic strategies targeting EED and PRC2-mediated diseases. Its potent inhibitory effects on H3K27 trimethylation make it a promising candidate for further research and application in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 1951408-58-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,5,1,4,0 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1951408-58:
(9*1)+(8*9)+(7*5)+(6*1)+(5*4)+(4*0)+(3*8)+(2*5)+(1*8)=184
184 % 10 = 4
So 1951408-58-4 is a valid CAS Registry Number.
1951408-58-4Relevant articles and documents
CRYSTALLINE FORMS OF TRIAZOLOPYRIMIDINE COMPOUND
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Paragraph 00162, (2018/04/11)
Provided herein are crystalline forms of a triazolopyrimidine compound, which is useful for treating a PRC2-mediated disease or disorder.
TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF
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Paragraph 0521; 0523, (2016/07/27)
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.
