1952-82-5Relevant academic research and scientific papers
Phenolic structure and colour in Mannich reaction products
Tyman, John H.P.,Patel, Mahesh
, p. 34 - 37 (2008/02/02)
Mannich reactions have been carried out with a variety of model alkylphenols and dimethylamine, methylamine, and diethylenetriamine to trace the origin of persistent coloured products occurring in related reactions with pentadeca(e)nylphenol and 4-tert-alkylphenols. It was found to be attributable to the presence of resorcinolic impurities.
Synthesis of the β2 Agonist (R)-Salmeterol Using a Sequence of Supported Reagents and Scavenging Agents
Bream, Robert N.,Ley, Steven V.,Procopiou, Panayiotis A.
, p. 3793 - 3796 (2007/10/03)
(Matrix Presented) The enantioselective synthesis of (R)-salmeterol has been achieved by using a sequence of supported reagents and sequestering agents. The saligenin core was installed by a regiospecific alkylation and a chiral auxiliary approach was employed to introduce the desired stereochemistry via a diastereoselective reduction.
