195528-81-5Relevant academic research and scientific papers
Stereospecific coupling of α-aminoalkylcuprates with vinyl iodides
Dieter, R. Karl,Sharma, Ram R.
, p. 5937 - 5940 (1997)
Allylic amines can be prepared stereospecifically via a coupling reaction of vinyl iodides and α-aminoalkylcuprates prepared from the corresponding lithium reagents and LiCl solubilized CuCN. The reaction works well for both E and Z dialkyl substituted vinyl iodides. 1-Iodoalkynes can also be coupled in modest yields to afford propargyl amines.
